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Figure 1 | Cardiovascular Diabetology

Figure 1

From: Effects of icosapent ethyl on lipid and inflammatory parameters in patients with diabetes mellitus-2, residual elevated triglycerides (200–500 mg/dL), and on statin therapy at LDL-C goal: the ANCHOR study

Figure 1

Median placebo-adjusted percent change from baseline to week 12 for efficacy end points in diabetes subgroups by median baseline A 1c . A) IPE 4 g/day; B) IPE 2 g/day. *P ≤ 0.0001; P < 0.001; P < 0.01; §P ≤ 0.05. A1c = glycosylated hemoglobin A1c; Apo B = apolipoprotein B; HDL-C = high-density lipoprotein cholesterol; hsCRP = high-sensitivity C-reactive protein; IPE = icosapent ethyl; LDL-C = low-density lipoprotein cholesterol; Lp-PLA2 = lipoprotein-associated phospholipase A2; non–HDL-C = non-high-density lipoprotein cholesterol; NS = not significant; Ox-LDL = oxidized low-density lipoprotein; RLP-C = remnant-like particle cholesterol; TC = total cholesterol; TG = triglyceride; VLDL-C = very-low-density lipoprotein cholesterol; VLDL-TG = very-low-density lipoprotein triglycerides.

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