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Table 2 Correlation coefficients between L_RHI and markers of diabetic control and various nonglycemic metabolic variables

From: Relationship between fluctuations in glucose levels measured by continuous glucose monitoring and vascular endothelial dysfunction in type 2 diabetes mellitus

  HbA1c Averagea SDa MAGEa MPPGEa Time at LDL-C HDL-C TG SBP DBP
  <70a(n=12) ≥140a ≥200a
Averagea (n=57) 0.14             
SDa (n=57) −0.16 0.36**            
MAGEa (n=57) −0.06 0.30* 0.79**           
MMPGEa (n=57) 0.01 0.37** 0.64** 0.58**          
Time at <70a with hypoglycemia (n=12) 0.29 −0.69** −0.38 −0.70* −0.19         
Time at ≥140a (n=57) 0.12 0.84** 0.27* 0.18 0.32* −0.68*        
Time at ≥200a (n=57) 0.14 0.95** 0.43** 0.37** 0.39* −0.70* 0.76**       
LDL-C (n=57) 0.26 −0.01 −0.23 −0.13 0.04 0.65* −0.10 −0.04      
HDL-C (n=57) −0.17 0.01 0.31* 0.04 0.19 0.03 0.17 0.05 0.06     
TG (n=57) 0.27* 0.05 −0.21 −0.03 0.06 −0.33 0.04 0.01 0.16 −0.28*    
SBP (n=57) −0.07 −0.25 −0.09 0.01 −0.03 −0.07 −0.19 −0.22 −0.07 −0.18 0.05   
DBP (n=57) 0.20 −0.20 −0.27* −0.12 −0.10 −0.07 −0.16 −0.22 0.09 −0.26* 0.17 0.65**  
L_RHI (n=57) 0.12 −0.24 −0.50** −0.57** −0.41** −0.59* −0.20 −0.29* 0.17 −0.14 0.01 0.11 0.09
  1. a Measured by the continuous glucose monitoring system.
  2. Data are results of Pearson correlation analysis for normally distributed variables and Spearman rank correlation for variables with skewed distribution. *P<0.05, **P<0.01.
  3. Abbreviations: HbA1c hemoglobin A1c; SD standard deviation; MAGE, mean amplitude of glycemic excursions; MPPGE mean postprandial glucose excursions; LDL-C low-density lipoprotein cholesterol; HDL-C high-density lipoprotein cholesterol; TG triglyceride; SBP systolic blood pressure; DBP diastolic blood pressure; L_RHI the natural logarithmic scaled reactive hyperemia index.