GC-MS analysis and screening of antidiabetic, antioxidant and hypolipidemic potential of Cinnamomum tamala oil in streptozotocin induced diabetes mellitus in rats

Table 6 Effect of Cinnamomum tamala oil on glycosylated hemoglobin (HbA1c), hepatic glycogen and insulin

Treatment	Dose	HbA1c (% of Hb)	Hepatic glycogen (mg/g wt of tissue)	Insulin (micro U/ml)
Normal	--	6 ± 1.4	75 ± 6.7	15 ± 2.2
Diabetic Control	--	10.8 ± 2.3^a	28 ± 4.6^a	7.8 ± 1.2^a
CTO	100 mg/kg	9.0 ± 3.2	46 ± 2.3*	9.8 ± 2.2
CTO	200 mg/kg	7.4 ± 1.6**	62 ± 4.6**	12 ± 2.1*
Cinnamaldehyde	20 mg/kg	7.0 ± 0.6**	66 ± 2.3**	13 ± 1.6*
Glibenclamide	0.6 mg/kg	6.8 ± 0.9**	64 ± 3.4**	12.5 ± 1.8*

Values are presented as mean ± S.E.M; n = 6 in each group. One way ANOVA followed by Dunnett’s test ^ap < 0.01 vs. normal; *p < 0.05; **p < 0.01 vs. diabetic control; CTO: Cinnamomum tamala oil.

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