Top panel: representative slides showing immunohistochemical staining of CTGF (stained in brown as shown by arrow) in the myocardium. Slides A, B, C represent control, diabetic and diabetic treated with telmisartan, respectively. Amplifications × 400. Bottom: bar graph shows quantitative analysis of myocardial CTGF expression in control and diabetic rats treated with or without telmisartan. Control (C), diabetic (D), diabetic treated (DT). Data are expressed as mean ± S.E.M (n = 10 per group). * P <0.05 different from control, # P <0.05 different from diabetic.