Top panel: representative slides showing Masson's trichrome staining (Myocardial collagen stained in blue as shown by arrow) in the myocardium. Slides A, B, C represent control, diabetic and diabetic treated with telmisartan, respectively. Amplifications × 400. Bottom: bar graph shows quantitative analysis of myocardial collagen content in control and diabetic rats treated with or without telmisartan. Control (C), diabetic (D), diabetic treated (DT). Data are expressed as mean ± S.E.M (n = 10 per group). * P <0.05 different from control, # P <0.05 different from diabetic.