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Table 1 Baseline characteristics of the study participants

From: Potential association between coronary artery disease and the inflammatory biomarker YKL-40 in asymptomatic patients with type 2 diabetes mellitus

 

Suspected CAD (n = 41)

No evidence of CAD (n = 29)

p-value

Age (years)

60 ± 5

58 ± 6

0.237

Male (n,%)

19 (46.3)

9 (31.0)

0.149

Body-mass index (kg/m2)

25.7 ± 3.3

26.4 ± 3.6

0.468

SBP (mmHg)

131 ± 18

122 ± 17

0.066

DBP(mmHg)

74 ± 10

71 ± 8

0.305

Diabetes duration (years)

9.1 ± 7.1

8.7 ± 6.1

0.813

Hypertension (n,%)

29 (70.7)

19 (65.5)

0.418

Dyslipidemia (n,%)

18 (62.1)

27 (65.9)

0.47

Family history of CAD (n,%)

25 (61.0)

17 (58.6)

0.519

Smoking Hx (n,%)

  

0.064

Never smoker

29 (70.7)

25 (86.2)

 

Ex-smoker

4 (9.8)

3 (10.3)

 

Current smoker

8 (19.5)

1 (3.4)

 

FPG (mg/dL)

132 ± 46

136 ± 41

0.718

PPG-2 hrs (mg/dL)

219 ± 104

196 ± 90

0.331

HbA1c (%)

7.49 ± 1.24

7.14 ± 1.19

0.398

GA (%)

19.7 ± 6.8

18.4 ± 4.9

0.362

hsCRP (mg/dL)

2.75 ± 5.39

1.83 ± 2.23

0.335

Total cholesterol (mg/dL)

175 ± 50

166 ± 43

0.414

LDL cholesterol (mg/dL)

100 ± 37

94 ± 39

0.585

HDL cholesterol (mg/dL)

45 ± 11

46 ± 12

0.745

TG (mg/dL)

130 ± 76

118 ± 44

0.41

Postprandial TG (mg/dL)

124 ± 60

112 ± 43

0.352

HOMAIR

5.25 ± 6.51

4.18 ± 3.10

0.364

Framingham risk score (FRS)

7.3 ± 5.6

5.2 ± 6.3

0.18

CACS

206 ± 342

3 ± 13

0.003

Chemerin (ng/mL)

201.3 ± 82.3

193.1 ± 75.9

0.674

Omentin (ng/mL)

104.4 ± 29.4

106.4 ± 23.5

0.767

YKL-40 (ng/mL)

148.6 ± 82.3

96.7 ± 73.0

0.013

sCD26 (ng/mL)

381.5 ± 399.4

332.0 ± 188.9

0.494

Insulin (%)

12 (29.3)

9 (31.0)

0.54

Sulfonylurea (%)

18 (43.9)

14 (48.3)

0.453

Metformin (%)

29 (70.7)

24 (82.8)

0.192

Thiazolidinedione (%)

12 (29.3)

7 (24.1)

0.423

ARB or ACE inhibitors (%)

26 (63.4)

12 (41.4)

0.057

Calcium channer blockers (%)

10 (24.4)

6 (20.7)

0.474

Beta blockers (%)

5 (12.2)

2 (6.9)

0.381

Statins (%)

22 (53.7)

15 (51.7)

0.533

  1. DM, diabetes mellitus; CAD, coronary artery disease; SBP, systolic blood pressure; DBP, diastolic blood pressure; FPG, fasting plasma glucose; PPG-2 hrs, postprandial plasma glucose-2 hrs; HbA1c, glycated hemoglobin; GA, glycated albumin; hsCRP, high-sensitive C-reactive protein; LDL, ligh-density lipoprotein; HDL, high-density lipoprotein; TG, triglycerides; HOMA IR , homeostasis model assessment– insulin resistance; CACS, coronary artery calcium score; ARB, angiotensin receptor blocker; ACE, angiotensin converting enzyme.