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Table 1 Baseline characteristics of the study participants

From: Potential association between coronary artery disease and the inflammatory biomarker YKL-40 in asymptomatic patients with type 2 diabetes mellitus

  Suspected CAD (n = 41) No evidence of CAD (n = 29) p-value
Age (years) 60 ± 5 58 ± 6 0.237
Male (n,%) 19 (46.3) 9 (31.0) 0.149
Body-mass index (kg/m2) 25.7 ± 3.3 26.4 ± 3.6 0.468
SBP (mmHg) 131 ± 18 122 ± 17 0.066
DBP(mmHg) 74 ± 10 71 ± 8 0.305
Diabetes duration (years) 9.1 ± 7.1 8.7 ± 6.1 0.813
Hypertension (n,%) 29 (70.7) 19 (65.5) 0.418
Dyslipidemia (n,%) 18 (62.1) 27 (65.9) 0.47
Family history of CAD (n,%) 25 (61.0) 17 (58.6) 0.519
Smoking Hx (n,%)    0.064
Never smoker 29 (70.7) 25 (86.2)  
Ex-smoker 4 (9.8) 3 (10.3)  
Current smoker 8 (19.5) 1 (3.4)  
FPG (mg/dL) 132 ± 46 136 ± 41 0.718
PPG-2 hrs (mg/dL) 219 ± 104 196 ± 90 0.331
HbA1c (%) 7.49 ± 1.24 7.14 ± 1.19 0.398
GA (%) 19.7 ± 6.8 18.4 ± 4.9 0.362
hsCRP (mg/dL) 2.75 ± 5.39 1.83 ± 2.23 0.335
Total cholesterol (mg/dL) 175 ± 50 166 ± 43 0.414
LDL cholesterol (mg/dL) 100 ± 37 94 ± 39 0.585
HDL cholesterol (mg/dL) 45 ± 11 46 ± 12 0.745
TG (mg/dL) 130 ± 76 118 ± 44 0.41
Postprandial TG (mg/dL) 124 ± 60 112 ± 43 0.352
HOMAIR 5.25 ± 6.51 4.18 ± 3.10 0.364
Framingham risk score (FRS) 7.3 ± 5.6 5.2 ± 6.3 0.18
CACS 206 ± 342 3 ± 13 0.003
Chemerin (ng/mL) 201.3 ± 82.3 193.1 ± 75.9 0.674
Omentin (ng/mL) 104.4 ± 29.4 106.4 ± 23.5 0.767
YKL-40 (ng/mL) 148.6 ± 82.3 96.7 ± 73.0 0.013
sCD26 (ng/mL) 381.5 ± 399.4 332.0 ± 188.9 0.494
Insulin (%) 12 (29.3) 9 (31.0) 0.54
Sulfonylurea (%) 18 (43.9) 14 (48.3) 0.453
Metformin (%) 29 (70.7) 24 (82.8) 0.192
Thiazolidinedione (%) 12 (29.3) 7 (24.1) 0.423
ARB or ACE inhibitors (%) 26 (63.4) 12 (41.4) 0.057
Calcium channer blockers (%) 10 (24.4) 6 (20.7) 0.474
Beta blockers (%) 5 (12.2) 2 (6.9) 0.381
Statins (%) 22 (53.7) 15 (51.7) 0.533
  1. DM, diabetes mellitus; CAD, coronary artery disease; SBP, systolic blood pressure; DBP, diastolic blood pressure; FPG, fasting plasma glucose; PPG-2 hrs, postprandial plasma glucose-2 hrs; HbA1c, glycated hemoglobin; GA, glycated albumin; hsCRP, high-sensitive C-reactive protein; LDL, ligh-density lipoprotein; HDL, high-density lipoprotein; TG, triglycerides; HOMA IR , homeostasis model assessment– insulin resistance; CACS, coronary artery calcium score; ARB, angiotensin receptor blocker; ACE, angiotensin converting enzyme.
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