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Table 2 Characteristics of participants and incidence of CHD and IS according to FPG and 2hPG categories

From: Development of coronary heart disease and ischemic stroke in relation to fasting and 2-hour plasma glucose levels in the normal range

  Men Women
Group I Group II Group I Group II
2hPG ≤ FPG 2hPG > FPG 2hPG ≤ FPG 2hPG > FPG
no. (%) 1818 (48.6) 1925 (51.4) 1110 (28.3) 2806 (71.7)
Age (years) 50 (0.28) * 57 (0.27) 49 (0.25) * 53 (0.16)
Body mass index (kg/m2) 25.9 (0.08) * 26.3 (0.07) 25.6 (0.13) 25.9 (0.08)
FPG (mmol/l) 5.33 (0.01) * 5.18 (0.01) 5.23 (0.01) * 5.18 (0.01)
2hPG (mmol/l) 4.42 (0.02) * 6.23 (0.02) 4.55 (0.02) * 6.37 (0.01)
Fasting insulin (ρmol/l) −0.07 (0.03) *† 0.09 (0.03) −0.13 (0.04) * 0.04 (0.03)
HOMA-IR −0.04 (0.03)*† 0.10 (0.03) −0.13 (0.04)* 0.01 (0.03)
Total serum cholesterol (mmol/l) 6.11 (0.03) 6.06 (0.03) 6.07 (0.03) 6.08 (0.02)
Blood pressure (mmHg)
 Systolic 138 (0.42) * 141 (0.41) 133 (0.59) 135 (0.37)
 Diastolic 84 (0.25) * 86 (0.25) 82 (0.32) * 83 (0.20)
Current smoking (%) 32.9 * 23.3 24.8 * 18.9
Hypertension (%) 48.7 * 64.2 45.0 * 51.7
Incidence per1000 person-years (no.)
 CHD 6.7 (225) 7.9 (241) 1.3 (24) 1.9 (91)
 IS 2.8 (96) * 4.5 (139) 1.4 (25) 1.7 (81)
 CHD + IS 8.7 (293) * 11.3 (345) 2.6 (48) 3.5 (165)
  1. Data are age- and cohort- adjusted means (standard error) or as noted. *p < 0.05 for difference between the two glucose groups in men or in women; Z-score for 2443 men and 1639 women who had fasting insulin measurements. CHD, coronary heart disease; FPG, fasting plasma glucose; 2hPG, 2-hour plasma glucose; HOMA-IR, homeostasis model assessment of insulin resistance; IS, ischemic stroke.