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Table 2 Characteristics of participants and incidence of CHD and IS according to FPG and 2hPG categories

From: Development of coronary heart disease and ischemic stroke in relation to fasting and 2-hour plasma glucose levels in the normal range

 

Men

Women

Group I

Group II

Group I

Group II

2hPG ≤ FPG

2hPG > FPG

2hPG ≤ FPG

2hPG > FPG

no. (%)

1818 (48.6)

1925 (51.4)

1110 (28.3)

2806 (71.7)

Age (years)

50 (0.28) *

57 (0.27)

49 (0.25) *

53 (0.16)

Body mass index (kg/m2)

25.9 (0.08) *

26.3 (0.07)

25.6 (0.13)

25.9 (0.08)

FPG (mmol/l)

5.33 (0.01) *

5.18 (0.01)

5.23 (0.01) *

5.18 (0.01)

2hPG (mmol/l)

4.42 (0.02) *

6.23 (0.02)

4.55 (0.02) *

6.37 (0.01)

Fasting insulin (ρmol/l)

−0.07 (0.03) *†

0.09 (0.03)

−0.13 (0.04) *

0.04 (0.03)

HOMA-IR

−0.04 (0.03)*†

0.10 (0.03)

−0.13 (0.04)*

0.01 (0.03)

Total serum cholesterol (mmol/l)

6.11 (0.03)

6.06 (0.03)

6.07 (0.03)

6.08 (0.02)

Blood pressure (mmHg)

 Systolic

138 (0.42) *

141 (0.41)

133 (0.59)

135 (0.37)

 Diastolic

84 (0.25) *

86 (0.25)

82 (0.32) *

83 (0.20)

Current smoking (%)

32.9 *

23.3

24.8 *

18.9

Hypertension (%)

48.7 *

64.2

45.0 *

51.7

Incidence per1000 person-years (no.)

 CHD

6.7 (225)

7.9 (241)

1.3 (24)

1.9 (91)

 IS

2.8 (96) *

4.5 (139)

1.4 (25)

1.7 (81)

 CHD + IS

8.7 (293) *

11.3 (345)

2.6 (48)

3.5 (165)

  1. Data are age- and cohort- adjusted means (standard error) or as noted. *p < 0.05 for difference between the two glucose groups in men or in women; Z-score for 2443 men and 1639 women who had fasting insulin measurements. CHD, coronary heart disease; FPG, fasting plasma glucose; 2hPG, 2-hour plasma glucose; HOMA-IR, homeostasis model assessment of insulin resistance; IS, ischemic stroke.