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Table 2 Linkage evidence for combined each two or all three diseases of 2DM, obesity and CAD

From: Identification of shared genetic susceptibility locus for coronary artery disease, type 2 diabetes and obesity: a meta-analysis of genome-wide studies

 

2DM/CAD

2DM/Obesity

Pos

Bin

Cytogenetic band

P SR

Bin

Cytogenetic band

P SR

1

9.3

9p21.1-q21.32

0.002362

16.3

16q12.2-q23.1

4.75E-05

2

6.2

6p22.3-p21.1

0.005861

4.5

4q24-q28.3

0.000159

3

7.4

7q12.11-q31.1

0.022381

9.3

9p21.1-q21.32

0.000543

4

16.3

16q12.2-q23.1

0.022471

6.5

6q23.2-q25.3

0.003457

5

4.1

4pter-p15.33

0.024538

2.3

2p23.2-p16.2

0.00572

6

22.2

22q12.3-pter

0.030478

4.4

4q13.3-q24

0.010083

7

17.2

17p12-q21.33

0.045176

12.3

12p11.21-q15

0.029702

 

CAD/Obesity

All three diseases

Pos

Bin

Cytogenetic band

P SR

Bin

Cytogenetic band

P SR

1

16.3

16q12.2-q23.1

0.006016

9.3

9p21.1-q21.32

0.000276

2

6.5

6q23.2-q25.3

0.006592

16.3

16q12.2-q23.1

0.000505

3

16.2

16p13-q12.2

0.030775

6.5

6q23.2-q25.3

0.002055

4

9.3

9p21.1-q21.32

0.040512

4.5

4q24-q28.3

0.004021

5

10.5

10q23.33-q26.13

0.041678

7.3

7p14.1-q21.11

0.011893

6

11.2

11p15.1-p12

0.041838

3.6

3q22.1-q25.31

0.014341

7

4.5

4q24-q28.3

0.042347

4.4

4q13.3-q24

0.019338

8

7.3

7p14.1-q21.11

0.043952

11.3

11p12-q13.3

0.022461

  1. 2DM, type 2 diabetes; CAD, coronary artery disease.