Skip to main content

Table 1 Comparisons of body weight, renal function, blood pressure and left ventricular weight in the Wistar rat 8 weeks after subtotal nephrectomy (SNx)

From: Effects of olmesartan on arterial stiffness in rats with chronic renal failure

 

NC (n = 13)

CRF (n = 14)

CRF + OLM (n = 14)

 

mean ± SE

mean ± SE

mean ± SE

BW (g)

480 ± 11.9

412.1 ± 16.6*

443.6 ± 10.5

BUN (mg/dl)

19.35 ± 0.8

64.76 ± 3.35*

46.79 ± 2.72†

SCr (mg/dl)

0.66 ± 0.02

1.7 ± 0.1*

1.04 ± 0.09†

P s (mm Hg)

117.2 ± 2.2

178.5 ± 8.6*

135.7 ± 6.2†

P d (mm Hg)

94.2 ± 2.3

126.9 ± 5.2*

101.8 ± 6.1†

P m (mm Hg)

106.7 ± 2.3

152.1 ± 6.4*

119.2 ± 6.1†

PP (mm Hg)

23.0 ± 0.6

51.6 ± 4.4*

33.8 ± 2.2†

LVW (g)

0.98 ± 0.03

1.20 ± 0.04*

0.94 ± 0.05†

LVW/BW ( ‰)

2.04 ± 0.05

2.9 ± 0.11*

2.11 ± 0.08†

  1. NC, normal controls; CRF, chronic renal failure; OLM, olmesartan.
  2. Abbreviations: BW, body weight; Ps, aortic systolic pressure; Pd, aortic diastolic pressure; Pm, mean aortic pressure; PP, pulse pressure; LVW, left ventricular weight. * : P < 0.05, CRF vs. NC; † :P < 0.05, CRF + OLM vs. CRF.