Figure 5

Effects of HG and fasudil on RhoA and ROCKI protein in HUVECs. RhoA and ROCKI protein was determined by Western blot analysis. Each band density was normalized by its own control. A is representative the dose-dependent effects of HG and fasudil. B is representative time-dependent effects of HG and fasudil. C is the summary of data (means ± SD) from the dose-dependent experiments. * P < 0.05 when compared to control. # P < 0.05 when compared to HG (33 mM) alone. D and E is the summary of data (means ± SD) from the time-dependent experiments. * P < 0.05 when compared to time 0, # P < 0.05, when compared to HG alone.