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Table 1 Baseline Characteristics

From: Effects of Exenatide vs. Metformin on endothelial function in obese patients with pre-diabetes: a randomized trial

Variable

Metformin Group(N = 25)

Exenatide Group(N = 25)

P-Value

Age (years)

58.4 ± 10.1

58.7 ± 10.0

0.911

Gender (male/female)

7/18

5/20

0.742

BMI (kg/m2)

35.8 ± 7.0

35.3 ± 5.5

0.781

Waist Circumference (cm)

112.3 ± 15.7

111.6 ± 12.5

0.861

Body Fat (%)

44.5 ± 4.9

42.3 ± 6.5

0.264

SBP (mmHg)

125.8 ± 12.3

130.6 ± 17.1

0.260

DBP (mmHg)

75.6 ± 10.0

74.3 ± 9.3

0.620

Cholesterol (mg/dL)

185.0 ± 33.1

187.4 ± 28.7

0.782

LDL-Cholesterol (mg/dL)

101.9 ± 27.2

104.1 ± 26.9

0.777

HDL-Cholesterol (mg/dL)

53.2 ± 14.3

53.8 ± 11.9

0.864

Triglycerides (mg/dL)

137.2 ± 43.0

149.0 ± 58.4

0.419

Glucose (mg/dL)

103.1 ± 9.1

103.2 ± 9.9

0.976

Insulin (mU/L)

9.6 ± 8.1

8.5 ± 4.7

0.538

HOMA-IR

2.5 ± 2.4

2.2 ± 1.4

0.547

CRP (mg/L)

4.3 ± 2.2

4.9 ± 3.2

0.510

OxLDL (U/L)

142.8 ± 66.7

123.7 ± 61.4

0.301

VCAM-1 (ng/mL)

529.1 ± 178.6

495.5 ± 119.9

0.440

RHI

2.03 ± 0.66

2.03 ± 0.57

0.989

  1. BMI = body mass index; SBP = systolic blood pressure; DBP = diastolic blood pressure; LDL = low density lipoprotein; HDL = high density lipoprotein; HOMA-IR = homeostasis model assessment for insulin resistance; CRP = C-reactive protein; OxLDL = oxidized low density lipoprotein; VCAM-1 = vascular cell adhesion molecule-1; RHI = reactive hyperemic index.
  2. Body fat data were obtained in 35 patients (exenatide N = 17; metformin N = 18)
  3. Data are shown as mean ± standard deviation.