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Table 1 Baseline Characteristics

From: Effects of Exenatide vs. Metformin on endothelial function in obese patients with pre-diabetes: a randomized trial

Variable Metformin Group(N = 25) Exenatide Group(N = 25) P-Value
Age (years) 58.4 ± 10.1 58.7 ± 10.0 0.911
Gender (male/female) 7/18 5/20 0.742
BMI (kg/m2) 35.8 ± 7.0 35.3 ± 5.5 0.781
Waist Circumference (cm) 112.3 ± 15.7 111.6 ± 12.5 0.861
Body Fat (%) 44.5 ± 4.9 42.3 ± 6.5 0.264
SBP (mmHg) 125.8 ± 12.3 130.6 ± 17.1 0.260
DBP (mmHg) 75.6 ± 10.0 74.3 ± 9.3 0.620
Cholesterol (mg/dL) 185.0 ± 33.1 187.4 ± 28.7 0.782
LDL-Cholesterol (mg/dL) 101.9 ± 27.2 104.1 ± 26.9 0.777
HDL-Cholesterol (mg/dL) 53.2 ± 14.3 53.8 ± 11.9 0.864
Triglycerides (mg/dL) 137.2 ± 43.0 149.0 ± 58.4 0.419
Glucose (mg/dL) 103.1 ± 9.1 103.2 ± 9.9 0.976
Insulin (mU/L) 9.6 ± 8.1 8.5 ± 4.7 0.538
HOMA-IR 2.5 ± 2.4 2.2 ± 1.4 0.547
CRP (mg/L) 4.3 ± 2.2 4.9 ± 3.2 0.510
OxLDL (U/L) 142.8 ± 66.7 123.7 ± 61.4 0.301
VCAM-1 (ng/mL) 529.1 ± 178.6 495.5 ± 119.9 0.440
RHI 2.03 ± 0.66 2.03 ± 0.57 0.989
  1. BMI = body mass index; SBP = systolic blood pressure; DBP = diastolic blood pressure; LDL = low density lipoprotein; HDL = high density lipoprotein; HOMA-IR = homeostasis model assessment for insulin resistance; CRP = C-reactive protein; OxLDL = oxidized low density lipoprotein; VCAM-1 = vascular cell adhesion molecule-1; RHI = reactive hyperemic index.
  2. Body fat data were obtained in 35 patients (exenatide N = 17; metformin N = 18)
  3. Data are shown as mean ± standard deviation.