TY - JOUR AU - Aerni-Flessner, Lauren AU - Abi-Jaoude, Melissa AU - Koenig, Amanda AU - Payne, Maria AU - Hruz, Paul W. PY - 2012 DA - 2012/06/08 TI - GLUT4, GLUT1, and GLUT8 are the dominant GLUT transcripts expressed in the murine left ventricle JO - Cardiovascular Diabetology SP - 63 VL - 11 IS - 1 AB - The heart derives energy from a wide variety of substrates including fatty acids, carbohydrates, ketones, and amino acids. The healthy heart generates up to 30% of its ATP from glucose. Under conditions of cardiac injury or stress, the heart relies even more heavily on glucose as a source of fuel. Glucose is transported into the heart by members of the family of facilitative glucose transporters (GLUTs). While research examining the transport of glucose into the heart has primarily focused on the roles of the classical glucose transporters GLUT1 and GLUT4, little is known about the functions of more newly identified GLUT isoforms in the myocardium. SN - 1475-2840 UR - https://doi.org/10.1186/1475-2840-11-63 DO - 10.1186/1475-2840-11-63 ID - Aerni-Flessner2012 ER -