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Figure 1 | Cardiovascular Diabetology

Figure 1

From: Increased myocardial SERCA expression in early type 2 diabetes mellitus is insulin dependent: In vivo and in vitro data

Figure 1

In vivo data: Expression of SERCA 2a and PLB in left ventricular tissue from non-diabetic control rats (n = 7), Zucker Diabetes Fatty (ZDF) rats (n = 7) and ZDF (n = 6) rats treated with insulin. (A) Shows a representative Northern blot of SERCA and phospholamban (lane 1 = left ventricular tissue from control rats, lane 2 = left ventricular tissue from diabetic ZDF rats; lane 3 = left ventricular tissue from ZDF rats treated with insulin). Arrow depicts the position of the 28 S ribosomal RNA. (B) quantitative analysis and (C) SERCA2a/PLB ratio. Values are given in mean ± SEM. *p < 0.05 vs. control; #p < 0.05 vs. ZDF.

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