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Table 2 Effect of the prostacyclin analogue iloprost (1 μM) in the ex vivo ADP-induced washed platelet aggregation

From: Platelet hyperaggregability in high-fat fed rats: A role for intraplatelet reactive-oxygen species production

 

SCD

HFD

Control

54.2 ± 2.9%

70.7 ± 4.9%#

Iloprost

5.5 ± 1.5%*

5.7 ± 2.2%*

  1. Male Wistar rats were fed with either a standard chow diet (SCD, n = 4) or high-fat diet (HFD, n = 4) during 10 weeks.
  2. *P < 0.05 compared with respective untreated platelets. #P < 0.05 compared with untreated platelets in SCD group.