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Table 1 Mean Arterial Pressure

From: Hyperglycemia raises the threshold of levosimendan- but not milrinone-induced postconditioning in rat hearts

 

Number

Baseline

Preocclusion

Occlusion

30 min

 

Reperfusion

     

5 min

30 min

1 hr

2 hr

MAP (mmHg)

        

   CON

14

99 ± 24

97 ± 14

93 ± 20

95 ± 26

109 ± 28

107 ± 31

100 ± 36

   MIL10

8

91 ± 24

88 ± 26

91 ± 23

84 ± 25

100 ± 26

104 ± 20

107 ± 15

   MIL30

9

98 ± 14

83 ± 14

91 ± 16

88 ± 22

103 ± 17

99 ± 30

99 ± 31

   LEV3

7

97 ± 20

95 ± 16

84 ± 27

87 ± 12

92 ± 16

99 ± 14

106 ± 14

   LEV10

9

90 ± 16

84 ± 13

79 ± 28*

80 ± 23*

89 ± 32

93 ± 26

96 ± 22

   HGCON

10

109 ± 21

107 ± 23

93 ± 20

92 ± 23

102 ± 26

110 ± 23

112 ± 20

   HG MIL30

7

101 ± 13

102 ± 12

92 ± 13

93 ± 11

101 ± 14

109 ± 18

118 ± 19

   HG LEV10

9

101 ± 16

91 ± 9

85 ± 10

84 ± 11

94 ± 15

104 ± 17

108 ± 18

   HG LEV30

7

105 ± 21

97 ± 11

96 ± 18

93 ± 15

93 ± 12

106 ± 9

104 ± 18

   HG LEV100

7

103 ± 18

109 ± 12

79 ± 12*

81 ± 9*

84 ± 13

96 ± 14

94 ± 21

   ATR

6

103 ± 13

96 ± 13

108 ± 11

107 ± 15

113 ± 19

113 ± 16

116 ± 12

   MIL30 + ATR

8

101 ± 14

93 ± 21

97 ± 14

97 ± 15

101 ± 15

101 ± 16

102 ± 11

   LEV10 + ATR

7

87 ± 15

85 ± 15

97 ± 22

95 ± 17

97 ± 24

98 ± 20

96 ± 18

   HG MIL30 + ATR

7

98 ± 20

95 ± 17

98 ± 19

100 ± 20

103 ± 21

103 ± 17

88 ± 17

   HG LEV100 + ATR

9

93 ± 14

97 ± 18

89 ± 21

88 ± 17

98 ± 21

103 ± 23

101 ± 25

  1. Data are mean ± SD.
  2. MAP = mean arterial pressure; CON = control; MIL10 or 30 = 10 or 30 μg/kg milrinone; LEV 3, 10, 30 or 100 = 3, 10, 30 or 100 μg/kg levosimendan; HG = hyperglycemia; ATR = atractyloside.
  3. *Significantly (P < 0.05) different from baseline.
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Cardiovascular Diabetology

ISSN: 1475-2840