Reduced lung function is independently associated with increased risk of type 2 diabetes in Korean men

Table 4 Multivariable logistic regression analysis for the association between lung function and incident type 2 diabetes in non-obese subjects (BMI < 25) during a five-year follow-up

	Type 2 diabetes	Model 1		Model 2		Model 3
	n (%)	OR[95% CI]	P	OR[95% CI]	P	OR[95% CI]	P
FVC
Q 1	23 (1.7)	2.15[1.02-4.57]	0.045	2.06[0.97-4.38]	0.061	1.93[0.90-4.12]	0.091
Q 2	16 (1.2)	1.60[0.72-3.54]	0.247	1.55[0.70-3.45]	0.279	1.47[0.66-3.28]	0.346
Q 3	15 (1.1)	1.50[0.67-3.36]	0.322	1.53[0.68-3.42]	0.305	1.51[0.67-3.41]	0.317
Q 4	10 (0.7)	1		1		1
P value	0.142^*
FEV₁
Q 1	24 (1.8)	2.19[1.09-4.42]	0.028	2.06[1.02-4.17]	0.044	1.87[0.92-3.80]	0.084
Q 2	14 (1.0)	1.30[0.60-2.83]	0.508	1.25[0.57-2.72]	0.581	1.17[0.53-2.57]	0.694
Q 3	14 (1.0)	1.23[0.56-2.66]	0.608	1.23[0.56-2.68]	0.602	1.19[0.54-2.60]	0.665
Q 4	12 (0.9)	1		1		1
P value	0.135^*

^*P value was obtained from Chi-square tests for the comparison of incident diabetes among quartiles of FVC (% predicted) and FEV₁ (% predicted).
Model 1 was adjusted for age and BMI.
Model 2 was adjusted as in model 1 plus education, smoking, exercise, alcohol and insulin.
Model 3 was adjusted as in model 1 plus education, smoking, exercise, alcohol, HOMA-IR, TC, TG, and HDL-C.
FEV1, forced expiratory volume in one second; FVC, forced vital capacity; OR, odds ratio; CI, confidence interval; BMI, body mass index; HOMA-IR, homeostasis model assessment – insulin resistance; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol.

ISSN: 1475-2840