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Table 3 Multivariable logistic regression analysis for the association between lung function and incident type 2 diabetes during a five-year follow-up

From: Reduced lung function is independently associated with increased risk of type 2 diabetes in Korean men

  Type 2 diabetes Model 1 Model 2 Model 3
  n (%) OR[95% CI] P OR[95% CI] P OR[95% CI] P
FVC        
Q 1 84 (3.6) 2.18[1.42-3.32] <0.0001 2.00[1.30-3.07] 0.002 1.84[1.19-2.84] 0.006
Q 2 40 (1.7) 1.18[0.73-1.91] 0.487 1.16[0.72-1.87] 0.548 1.11[0.69-1.80] 0.665
Q 3 52 (2.3) 1.67[1.06-2.62] 0.026 1.64[1.04-2.59] 0.032 1.66[1.05-2.62] 0.030
Q 4 31 (1.3) 1   1   1  
P value <0.0001*       
FEV1        
Q 1 72 (3.1) 1.95[1.31-2.92] 0.001 1.78[1.18-2.67] 0.006 1.58[1.04-2.39] 0.030
Q 2 53 (2.3) 1.59[1.04-2.43] 0.032 1.54[1.01-2.36] 0.047 1.46[0.95-2.25] 0.082
Q 3 43 (1.9) 1.20[0.77-1.86] 0.428 1.14[0.73-1.79] 0.555 1.08[0.69-1.70] 0.734
Q 4 39 (1.7) 1   1   1  
P value 0.005*       
  1. *P value was obtained from Chi-square tests for the comparisons of the incident diabetes among quartiles of FVC (% predicted) and FEV1 (% predicted).
  2. Model 1 was adjusted for age and BMI.
  3. Model 2 was adjusted as in model 1 plus education, smoking, exercise, alcohol and insulin.
  4. Model 3 was adjusted as in model 1 plus education, smoking, exercise, alcohol, HOMA-IR, TC, TG, and HDL-C.
  5. FEV1, forced expiratory volume in one second; FVC, forced vital capacity; OR, odds ratio; CI, confidence interval; BMI, body mass index; HOMA-IR, homeostasis model assessment – insulin resistance; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol.