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Table 3 Multivariable logistic regression analysis for the association between lung function and incident type 2 diabetes during a five-year follow-up

From: Reduced lung function is independently associated with increased risk of type 2 diabetes in Korean men

 

Type 2 diabetes

Model 1

Model 2

Model 3

 

n (%)

OR[95% CI]

P

OR[95% CI]

P

OR[95% CI]

P

FVC

       

Q 1

84 (3.6)

2.18[1.42-3.32]

<0.0001

2.00[1.30-3.07]

0.002

1.84[1.19-2.84]

0.006

Q 2

40 (1.7)

1.18[0.73-1.91]

0.487

1.16[0.72-1.87]

0.548

1.11[0.69-1.80]

0.665

Q 3

52 (2.3)

1.67[1.06-2.62]

0.026

1.64[1.04-2.59]

0.032

1.66[1.05-2.62]

0.030

Q 4

31 (1.3)

1

 

1

 

1

 

P value

<0.0001*

      

FEV1

       

Q 1

72 (3.1)

1.95[1.31-2.92]

0.001

1.78[1.18-2.67]

0.006

1.58[1.04-2.39]

0.030

Q 2

53 (2.3)

1.59[1.04-2.43]

0.032

1.54[1.01-2.36]

0.047

1.46[0.95-2.25]

0.082

Q 3

43 (1.9)

1.20[0.77-1.86]

0.428

1.14[0.73-1.79]

0.555

1.08[0.69-1.70]

0.734

Q 4

39 (1.7)

1

 

1

 

1

 

P value

0.005*

      
  1. *P value was obtained from Chi-square tests for the comparisons of the incident diabetes among quartiles of FVC (% predicted) and FEV1 (% predicted).
  2. Model 1 was adjusted for age and BMI.
  3. Model 2 was adjusted as in model 1 plus education, smoking, exercise, alcohol and insulin.
  4. Model 3 was adjusted as in model 1 plus education, smoking, exercise, alcohol, HOMA-IR, TC, TG, and HDL-C.
  5. FEV1, forced expiratory volume in one second; FVC, forced vital capacity; OR, odds ratio; CI, confidence interval; BMI, body mass index; HOMA-IR, homeostasis model assessment – insulin resistance; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol.