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Table 3 Genotype and Allele frequencies distribution of apoE gene polymorphism in controls, T2DM with and without CAD compared to healthy controls

From: Apolipoprotein E gene polymorphism: effects on plasma lipids and risk of type 2 diabetes and coronary artery disease

Genotype

Groups

 

Controls (n = 149)

T2DM (n = 155)

T2DM + CAD (n = 147)

E2/E2

0.013

0.006

0.006

E3/E3

0.758

0.754

0.598**

E4/E4

0.007

0.025

0.007

E2/E3

0.080

0.012*

0.074

E2/E4

0

0.006

0

E3/E4

0.140

0.193

0.321***

Allele ε2

0.05

0.02*

0.04

Allele ε3

0.87

0.86

0.79**

Allele ε4

0.07

0.13*

0.16††

  1. *p-value < 0.01 compared between controls and T2DM, **p-value < 0.01, ***p-value < 0.001 compared between controls and T2DM + CAD.
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Cardiovascular Diabetology

ISSN: 1475-2840