Genotype | Controls (n = 149) | T2DM (n = 155) | T2DM + CAD (n = 147) |
---|---|---|---|
E2/E2 | 2 (1.34%) | 1 (0.64%) | 1 (0.68%) |
E3/E3 | 113 (75.83%) | 117 (75.48%) | 88 (59.86%) |
E4/E4 | 1 (0.67%) | 4 (2.58%) | 1 (0.68%) |
E2/E3 | 12 (8.05%) | 2 (1.29%) | 11 (7.48%) |
E2/E4 | 0 (0%) | 1 (0.64%) | 0 (0%) |
E3/E4 | 21 (14.09%) | 30 (19.35%) | 46 (31.29%) |
p-value | 0.198 | 0.0001 | 0.157 |
Allele ε2(95% CI) | 0.05(0.03 - 0.08) | 0.02(0.01 - 0.04) | 0.04(0.02 - 0.07) |
Allele ε3(95% CI) | 0.87(0.82 - 0.90) | 0.86(0.81 - 0.89) | 0.79 (0.74 - 0.83) |
Allele ε4(95% CI) | 0.07(0.05 - 0.11) | 0.13 (0.09 - 0.16) | 0.16 (0.12 - 0.21) |