Figure 4

Percent changes in left ventricular developed pressure during ischemia and reperfusion in hearts from non-diabetic db/+ mice (closed circles, n = 9), diabetic db/db mice (closed triangles, n = 9), non-diabetic db/+ mice that received cariporide (open circles, n = 8), and diabetic db/db mice that received cariporide (open triangles, n = 8). *p < 0.05 vs. db/+, **p < 0.01 vs. db/+, ^†p < 0.05 vs. without cariporide, ^††p < 0.01 vs. without cariporide.