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Table 6 Risk for tertiary individual CV endpoints with linagliptin versus total comparators based on Cox hazard model

From: Cardiovascular safety with linagliptin in patients with type 2 diabetes mellitus: a pre-specified, prospective, and adjudicated meta-analysis of a phase 3 programme

 

Cox HR (95% CI)

CV death

0.74 (0.10-5.33)

Non-fatal MI

0.52 (0.17-1.54)

Non-fatal stroke

0.11 (0.02-0.51)

TIA

0.17 (0.02-1.53)

UAP with hospitalization

0.24 (0.02-2.34)

UAP without hospitalization

0.73 (0.04-12.02)

SAP

1.06 (0.44-2.58)

Total mortality

1.02 (0.23-4.63)

  1. CI, confidence interval; CV; cardiovascular; HR, hazard ratio; MI, myocardial infarction; SAP, stable angina pectoris; TIA, transient ischaemic attack; UAP, unstable angina pectoris.