| |
n
|
Baseline mean ± SD
|
After administration mean ± SD
|
Difference
|
Percentage
|
|---|
|
TC (mmol/L)
|
3316
|
5.76 ± 1,03
|
5.45 ± 0.94
|
-0.31 ± 1.00 §
|
-5.4%
|
|
LDL-C (mmol/L)
|
2226
|
3.19 ± 0.95
|
3.25 ± 0.81
|
0.05 ± 0.90 ‡
|
1.6%
|
|
TG (mmol/L)
|
3316
|
3.72 ± 2.45
|
2.03 ± 1.50
|
-1.69 ± 2.08 §
|
-45.4%
|
|
HDL-C (mmol/L)
|
2818
|
1.18 ± 0.32
|
1.34 ± 0.35
|
0.17 ± 0.25 §
|
14.0%
|
|
non-HDL-C (mmol/L)
|
2818
|
4.57 ± 0.99
|
4.11 ± 0.96
|
-0.46 ± 0.09 §
|
-10.1%
|
|
TG/HDL
|
1818
|
3.49 ± 2.75
|
1.70 ± 1.59
|
-1.79 ± 2.31 §
|
-51.3%
|
|
HbA1c (%)
|
3316
|
7.69 ± 1.52
|
7.22 ± 1.28
|
-0.47 ± 1.21 §
|
-6.2%
|
|
FBG (mmol/L)
|
2387
|
9.00 ± 3.46
|
7.81 ± 2.89
|
-1.19 ± 3.33 §
|
-13.2%
|
|
HOMA-R
|
102
|
4.46 ± 4.91
|
3.38 ± 3.83
|
-1.08 ± 4.78 †
|
-24.3%
|
- "Difference" indicates the value for the change from baseline. "Percentage" indicates rate of change from baseline. A paired t-test was used to assess statistically significant differences from baseline for each group. Symbols for p values in this and the tables that follow: †: p < 0.05, ‡: p < 0.01, §: p < 0.001
