Skip to main content

Advertisement

Table 4 Blood glucose concentration (mg/dl)

From: High-dose fasudil preserves postconditioning against myocardial infarction under hyperglycemia in rats: role of mitochondrial KATP channels

  Baseline Before ischemia Just after reperfusion 1 h after reperfusion 2 h after reperfusion
CON 88 ± 15 91 ± 19 112 ± 27 105 ± 32 101 ± 20
LF 95 ± 11 109 ± 14 122 ± 26 118 ± 26 100 ± 23
HF 89 ± 17 87 ± 13 111 ± 33 93 ± 35 95 ± 26
DIA 90 ± 14 88 ± 14 107 + 31 120 ± 35 107 ± 28
5HD 89 ± 12 85 ± 16 101 ± 28 108 ± 18 111 ± 28
HF + 5HD 87 ± 8 86 ± 9 105 ± 24 101 ± 26 104 ± 24
HG 92 ± 12 349 ± 32* 360 ± 50* 353 ± 28* 100 ± 39
LF + HG 92 ± 13 338 ± 24* 378 ± 57* 327 ± 29* 105 ± 42
HF + HG 92 ± 12 341 ± 25* 374 ± 52* 337 ± 47* 110 ± 28
DIA + HG 91 ± 13 349 ± 22* 350 ± 53* 353 ± 28* 106 ± 37
  1. Data are mean ± SD, and n = 10 for each.
  2. CON = control; LF or HF = 0.15 or 0.5 mg/kg fasudil hydrochloride; DIA = 10 mg/kg diazoxide; 5HD = 5-hydroxydecanoic acid; HG = hyperglycemia.
  3. *Significantly (p < 0.05) different from baseline.
  4. †Significantly (p < 0.05) different from control.