Skip to main content

Table 1 The classification of experimental groups

From: High-dose fasudil preserves postconditioning against myocardial infarction under hyperglycemia in rats: role of mitochondrial KATP channels

Groups

Treatments

CON

Saline, i.v. bolus just before reperfusion.

LF

Low-dose fasudil (0.15 mg/kg), i.v. bolus just before reperfusion.

HF

High-dose fasudil (0.5 mg/kg), i.v. bolus just before reperfusion.

DIA

Diazoxide (10 mg/kg), i.v. bolus just before reperfusion.

HG

Saline, i.v. bolus just before reperfusion, and continuous infusion of 50% glucose in water starting at 15 min before LAD occlusion and lasting until 60 min after reperfusion. The target blood glucose concentration was 350 mg/dl.

LF + HG

Same as group HG except for low-dose fasudil (0.15 mg/kg) in place of saline.

HF + HG

Same as group HG except for low-dose fasudil (0.5 mg/kg) in place of saline.

DIA + HG

Same as group HG except for diazoxide (10 mg/kg) in place of saline.

5HD

5HD (10 mg/kg), i.v. at 5 min before reperfusion followed by saline, i.v. bolus just before reperfusion.

HF + 5HD

Same as group 5HD except for high-dose fasudil (0.5 mg/kg) in place of saline.