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Table 4 Comparison of clinical features between subjects without and with visceral fat accumulation (VFA cutoff value 100 cm2) and hyperinsulinemia (IRI cutoff value 5.5 μIU/mL; median value) (Analysis 2) (n = 500)

From: Hyperinsulinemia correlates with low levels of plasma B-type natriuretic peptide in Japanese men irrespective of fat distribution

 

VFA < 100 cm2

 

VFA ≥ 100 cm2

 
 

IRI < 5.5 μIU/mL

IRI ≥ 5.5 μIU/mL

IRI < 5.5 μIU/mL

IRI ≥ 5.5 μIU/mL

Age, years

53 ± 11

47 ± 12*

56 ± 8*

54 ± 9†§

BMI, kg/m2

21.6 ± 2.0

23.1 ± 2.5*

23.9 ± 2.0*

25.9 ± 2.8†§

VFA, cm2

63 ± 26

72 ± 24

139 ± 28*

162 ± 40†§

SFA, cm2

92 ± 38

114 ± 58*

129 ± 37*

167 ± 55†§

Blood glucose, mg/dL

104 ± 14

110 ± 14

110 ± 23*

113 ± 17

Fasting IRI, μIU/mL

3.6 ± 1.1

7.1 ± 1.4*

4.2 ± 0.9*

9.8 ± 5.0†§

HbA1c (NGSP),%

5.6 ± 0.5

5.6 ± 0.5

5.8 ± 0.6*

5.9 ± 0.6

SBP, mmHg

118 ± 12

121 ± 13

123 ± 11*

125 ± 10

DBP, mmHg

75 ± 9

77 ± 7

78 ± 10*

80 ± 7§

Triglyceride, mg/dL

101 ± 63

108 ± 49

149 ± 111*

160 ± 96

HDL-cholesterol, mg/dL

62 ± 13

57 ± 10

58 ± 13*

52 ± 12†§

LDL-cholesterol, mg/dL

115 ± 29

124 ± 25

121 ± 28

127 ± 28

eGFR, mL/min

76 ± 12

79 ± 13

73 ± 12

73 ± 13

  1. Data are mean ± SD
  2. *p < 0.01, compared to with VFA < 100 cm2 and IRI < 5.5 μIU/mL
  3. p < 0.01, compared to with VFA < 100 cm2 and IRI ≥ 5.5 μIU/mL
  4. §p < 0.01 compared to with VFA ≥ 100 cm2 and IRI < 5.5 μIU/mL