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Table 4 Odd ratios of CAD to quartiles of TNF-α, IL-6 and nitrotyrosine after 75 g OGTT at 120 minutes

From: Postchallenge responses of nitrotyrosine and TNF-alpha during 75-g oral glucose tolerance test are associated with the presence of coronary artery diseases in patients with prediabetes

   

Quartiles

 

P value‡

Characteristics

1

2

3

4

TNF-α (120) (pg/ml)

< 6.0

6.0-6.8

6.8-7.6

> 7.6

 

   No. of CAD

13

16

15

21

 

   No. of Non-CAD

15

20

9

11

 

Crude OR

1.0

1.3 (0.7-2.3)

1.5 (0.8-4.5)

2.5 (1.3-6.9)*

< 0.05

Adjusted OR†

1.0

1.2 (0.5-2.1)

1.4 (0.7-3.1)

1.9 (0.9-3.3)

0.053

   

Quartiles

 

P value‡

 

1

2

3

4

IL-6 (120) (pg/ml)

< 4.0

4.0-5.0

5.0-5.5

> 5.5

 

   No. Of CAD

14

15

13

23

 

   No. of Non-CAD

18

22

10

5

 

Crude OR

1.0

1.1 (0.9-2.6)

1.5 (0.7-3.5)

1.9 (0.9-4.2)

0.078

Adjusted OR†

1.0

1.2 (0.8-2.1)

1.3 (0.8-2.9)

1.5 (0.7-3.9)

0.121

   

Quartiles

 

P value‡

 

1

2

3

4

NT (120) (μ mo/l)

< 0.70

0.70-0.90

0.91-1.10

≧ 1.10

 

   No. Of CAD

4

22

17

22

 

   No. of Non-CAD

7

23

16

9

 

Crude OR

1.0

1.5 (0.9-2.6)

2.7 (1.7-4.5)*

4.9 (2.7-8.6)*

< 0.01

Adjusted OR†

1.0

1.2 (0.7-2.1)

1.7 (0.8-3.6)

3.1 (2.2-5.3)*

< 0.05

  1. *P values < 0.05. Crude odd ratios (ORs) and confidence intervals (CIs) were calculated using logistic regression models comparing risk of each of the upper 3 quartiles for a given parameter to the lowest quartile. † Adjusted for age, gender, body mass index, smoking, lipid profiles, medication and glucose tolerance status by conditional logistic regression analysis. ‡P values for trend across quartiles