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Table 4 Odd ratios of CAD to quartiles of TNF-α, IL-6 and nitrotyrosine after 75 g OGTT at 120 minutes

From: Postchallenge responses of nitrotyrosine and TNF-alpha during 75-g oral glucose tolerance test are associated with the presence of coronary artery diseases in patients with prediabetes

    Quartiles   P value‡
Characteristics 1 2 3 4
TNF-α (120) (pg/ml) < 6.0 6.0-6.8 6.8-7.6 > 7.6  
   No. of CAD 13 16 15 21  
   No. of Non-CAD 15 20 9 11  
Crude OR 1.0 1.3 (0.7-2.3) 1.5 (0.8-4.5) 2.5 (1.3-6.9)* < 0.05
Adjusted OR† 1.0 1.2 (0.5-2.1) 1.4 (0.7-3.1) 1.9 (0.9-3.3) 0.053
    Quartiles   P value‡
  1 2 3 4
IL-6 (120) (pg/ml) < 4.0 4.0-5.0 5.0-5.5 > 5.5  
   No. Of CAD 14 15 13 23  
   No. of Non-CAD 18 22 10 5  
Crude OR 1.0 1.1 (0.9-2.6) 1.5 (0.7-3.5) 1.9 (0.9-4.2) 0.078
Adjusted OR† 1.0 1.2 (0.8-2.1) 1.3 (0.8-2.9) 1.5 (0.7-3.9) 0.121
    Quartiles   P value‡
  1 2 3 4
NT (120) (μ mo/l) < 0.70 0.70-0.90 0.91-1.10 1.10  
   No. Of CAD 4 22 17 22  
   No. of Non-CAD 7 23 16 9  
Crude OR 1.0 1.5 (0.9-2.6) 2.7 (1.7-4.5)* 4.9 (2.7-8.6)* < 0.01
Adjusted OR† 1.0 1.2 (0.7-2.1) 1.7 (0.8-3.6) 3.1 (2.2-5.3)* < 0.05
  1. *P values < 0.05. Crude odd ratios (ORs) and confidence intervals (CIs) were calculated using logistic regression models comparing risk of each of the upper 3 quartiles for a given parameter to the lowest quartile. † Adjusted for age, gender, body mass index, smoking, lipid profiles, medication and glucose tolerance status by conditional logistic regression analysis. ‡P values for trend across quartiles