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Table 3 Comparison of proinflammatory cytokines and oxidative markers before and after 75 g oral glucose tolerance test (75 g-OGTT) in patients categorized according to glucose tolerance status and the presence of CAD

From: Postchallenge responses of nitrotyrosine and TNF-alpha during 75-g oral glucose tolerance test are associated with the presence of coronary artery diseases in patients with prediabetes

  NGT (n = 50) IGT (n = 41) T2DM (n = 29)
  CAD (n = 18) Non-CAD (n = 32) CAD (n = 28) Non-CAD (n = 13) CAD (n = 19) Non-CAD (n = 10)
PG (mg/dl)       
PG-0 99 ± 11 98 ± 12 102 ± 11 100 ± 13 112 ± 13 108 ± 17
PG-30 163 ± 36 173 ± 43 175 ± 31 182 ± 13 203 ± 47 188 ± 34
PG-60 165 ± 44 165 ± 42 196 ± 38 204 ± 42 248 ± 60 216 ± 40
PG-90 152 ± 27 138 ± 28 187 ± 31 186 ± 21 257 ± 52 225 ± 43
PG-120 118 ± 15 112 ± 23 172 ± 17 170 ± 14 250 ± 51 246 ± 29
PG-150 114 ± 29 88 ± 23 148 ± 33 139 ± 19 204 ± 65 164 ± 57
PG-180 83 ± 26 85 ± 19 127 ± 40 104 ± 31 172 ± 69 167 ± 56
TNF-α (pg/ml)       
TNF-α (0) 3.8 (3.4-4.9) 3.8 (3.5-4.0) 3.9 (3.6-4.9) 3.6 (3.0-4.2) 3.8 (3.6-4.0) 3.9 (3.4-4.3)
TNF-α (60) 5.7 (5.1-5.9) 5.3 (5.0-5.8) 5.7 (5.4-6.1) 5.3 (5.2-5.9) 5.8 (5.5-5.9) 5.4 (5.3-6.7)
TNF-α (120) 6.4 (5.9-7.9) 6.5 (5.5-6.8) 7.5* (6.8-8.3) 6.4 (3.5-7.1) 7.6† (6.5-7.8) 6.2 (5.8-8.1)
IL-6 (pg/ml)       
IL-6 (0) 2.5 (2.2-3.4) 2.5(2.3-3.1) 3.2 (2.4-3.4) 3.0 (2.3-3.5) 2.5(2.0-3.4) 3.2(2.6-3.4)
IL-6 (60) 4.2(3.7-4.9) 4.0(3.9-4.2) 4.4 (3.7-5.0) 4.3 (3.7-4.6) 4.5(3.7-5.2) 4.3(3.8-4.6)
IL-6 (120) 4.7(4.4-5.0) 4.4(3.9-4.9) 5.0 (4.4-7.2) 4.4 (3.5-5.4) 5.2(3.0-5.8) 4.8(4.3-5.0)
NT (μ mol/l)       
NT (0) 0.23 (0.12-0.24) 0.17 (0.15-0.23) 0.17 (0.14-0.23) 0.18 (0.04-0.25) 0.20 (0.18-0.23) 0.17 (0.14-0.18)
NT (60) 0.34 (0.21-0.36) 0.33 (0.25-0.35) 0.33 (0.28-0.38) 0.35 (0.16-0.36) 0.35 (0.31-0.39) 0.29 (0.26-0.37)
NT (120) 0.92 (0.65-1.02) 0.84 (0.72-0.87) 0.98* (0.80-1.19) 0.88 (0.76-0.98) 1.02† (0.85-1.27) 0.87 (0.79-1.16)
  1. Data are displayed in mean ± SD or median (interquartile range); *p < 0.05 represents the significant differences between normal and CAD in IGT group; †P < 0.05 represents the significant differences between normal and CAD in T2DM group; IL-6: interleukin-6; NT: nitrotyrosine; PG: plasma glucose; TNF-α: tumor necrosis factor-alpha