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Table 3 Adjusted-odds ratio (95% CI) for carotid atherosclerosis according to quartile of uric acid and metabolic syndrome by gender

From: Uric acid is an independent risk factor for carotid atherosclerosis in a Japanese elderly population without metabolic syndrome

  Quartile of serum uric acid
Uric acid range
Men (mg/dL)
Women (mg/dL)
UA-1
0.8-4.3
0.5-3.8
UA-2
4.4-5.5
3.9-4.7
UA-3
5.6-6.8
4.8-6.0
UA-4
6.9-16.1
6.1-15.4
All subjects
   Men, N = 663 1 (reference) 1.06 (0.63-1.76) 1.75 (1.02-3.02) † 2.01 (1.12-3.60) †
   Women, N = 916 1 (reference) 1.44 (0.94-2.21) 1.29 (0.84-1.98) 2.10 (1.30-3.39)§
Subjects without metabolic syndrome (< 3 components of metabolic syndrome)
   Men, N = 483 1 (reference) 0.92 (0.51-1.67) 2.00 (1.03-3.87) † 2.54 (1.21-5.34) ‡
   Women, N = 599 1 (reference) 1.78 (1.06-3.00)† 1.41 (0.83-2.40) 2.54 (1.35-4.78)§
Subjects with metabolic syndrome (≥3 components of metabolic syndrome)
   Men, N = 180 1 (reference) 2.14 (0.67-6.81) 1.55 (0.50-4.83) 2.26 (0.72-7.10)
   Women, N = 317 1 (reference) 0.81 (0.36-1.79) 1.12 (0.51-2.49) 1.43 (0.62-3.27)
  1. CI, confidential interval. Adjusted for age, body mass index, smoking status, systolic blood pressure, diastolic blood pressure, antihypertensive medication, LDL-cholesterol, HDL-cholesterol, triglycerides, antilipidemic medication, fasting plasma glucose, antidiabetic medication, and history of cardiovascular disease. † P < 0.05; ‡ P < 0.01; § P < 0.005 vs. the first quartile (UA-1).