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Table 2 Carotid intima-media thickness of subjects according to quartile of uric acid and metabolic syndrome by gender

From: Uric acid is an independent risk factor for carotid atherosclerosis in a Japanese elderly population without metabolic syndrome

 

Quartile of serum uric acid

 

Uric acid range

Men (mg/dL)

Women(mg/dL)

UA-1

0.8-4.3

0.5-3.8

UA-2

4.4-5.5

3.9-4.7

UA-3

5.6-6.8

4.8-6.0

UA-4

6.9-16.1

6.1-15.4

P for trend*

All subjects

 

   Men, N = 663

1.02 ± 0.20 #

1.06 ± 0.26

1.03 ± 0.20 §

1.13 ± 0.27

< 0.001

   Women, N = 916

0.97 ± 0.18 #

0.98 ± 0.20 #

0.99 ± 0.19 §

1.06 ± 0.25

< 0.001

Subjects without metabolic syndrome (< 3 components of metabolic syndrome)

 

   Men, N = 483

1.01 ± 0.20 #

1.07 ± 0.29

1.03 ± 0.20 §

1.15 ± 0.28

< 0.001

   Women, N = 599

0.95 ± 0.18 §

0.97 ± 0.19 †

0.99 ± 0.20

1.04 ± 0.21

0.002

Subjects with metabolic syndrome (≥3 components of metabolic syndrome)

 

   Men, N = 180

1.07 ± 0.23

1.04 ± 0.14

1.05 ± 0.19

1.10 ± 0.24

0.487

   Women, N = 317

1.01 ± 0.18

0.99 ± 0.22 †

1.00 ± 0.19 †

1.10 ± 0.23

0.004

  1. † P < 0.05; § P < 0.005; # P < 0.001 vs. the fourth quartile (UA-4). *P-value: ANOVA and Dunnett's test was used for the pos hoc analysis.