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Table 2 Carotid intima-media thickness of subjects according to quartile of uric acid and metabolic syndrome by gender

From: Uric acid is an independent risk factor for carotid atherosclerosis in a Japanese elderly population without metabolic syndrome

  Quartile of serum uric acid  
Uric acid range
Men (mg/dL)
Women(mg/dL)
UA-1
0.8-4.3
0.5-3.8
UA-2
4.4-5.5
3.9-4.7
UA-3
5.6-6.8
4.8-6.0
UA-4
6.9-16.1
6.1-15.4
P for trend*
All subjects  
   Men, N = 663 1.02 ± 0.20 # 1.06 ± 0.26 1.03 ± 0.20 § 1.13 ± 0.27 < 0.001
   Women, N = 916 0.97 ± 0.18 # 0.98 ± 0.20 # 0.99 ± 0.19 § 1.06 ± 0.25 < 0.001
Subjects without metabolic syndrome (< 3 components of metabolic syndrome)  
   Men, N = 483 1.01 ± 0.20 # 1.07 ± 0.29 1.03 ± 0.20 § 1.15 ± 0.28 < 0.001
   Women, N = 599 0.95 ± 0.18 § 0.97 ± 0.19 † 0.99 ± 0.20 1.04 ± 0.21 0.002
Subjects with metabolic syndrome (≥3 components of metabolic syndrome)  
   Men, N = 180 1.07 ± 0.23 1.04 ± 0.14 1.05 ± 0.19 1.10 ± 0.24 0.487
   Women, N = 317 1.01 ± 0.18 0.99 ± 0.22 † 1.00 ± 0.19 † 1.10 ± 0.23 0.004
  1. P < 0.05; § P < 0.005; # P < 0.001 vs. the fourth quartile (UA-4). *P-value: ANOVA and Dunnett's test was used for the pos hoc analysis.