Skip to main content

Table 2 Risk of incident type 2 diabetes in 157 cases compared to 277 referents

From: Signs of dysregulated fibrinolysis precede the development of type 2 diabetes mellitus in a population-based study

 

OR

95% CI

p-value

Family history of T2DM

2.46

1.52 - 3.97

< 0.001

Smoking (daily vs non-smoker)

1.69

0.98 - 2.89

0.059

Physical activity (sedentary vs active)

0.94

0.44 - 2.02

0.878

Hypertension*

3.85

2.48 - 5.97

< 0.001

Systolic blood pressure

2.00

1.58 - 2.54

< 0.001

Diastolic blood pressure

1.93

1.51 - 2.47

< 0.001

Fasting plasma glucose

3.77

2.68 - 5.32

< 0.001

2-h plasma glucose

2.65

2.03 - 3.47

< 0.001

BMI

3.09

2.29 - 4.18

< 0.001

Triglycerides

2.38

1.84 - 3.07

< 0.001

CRP

1.91

1.51 - 2.42

< 0.001

tPA

2.63

1.96 - 3.54

< 0.001

PAI-1

2.33

1.79 - 3.03

< 0.001

tPA/PAI-1 complex

4.02

2.84 - 5.69

< 0.001

VWF

1.73

1.36 - 2.19

< 0.001

  1. * Blood pressure ≄ 140/90 and/or on antihypertensive medication.
  2. Conditional logistic regression analysis. OR and 95% CI, per 1 SD increment.
  3. Referents were matched for age and sex. Natural logarithm transformation was used for haemostatic markers, C-reactive protein and triglycerides.
  4. OR: odds ratio; CI: confidence interval; SD: standard deviation; BMI: body mass index; CRP: C-reactive protein; T2DM: type 2 diabetes mellitus; tPA: tissue plasminogen activator; PAI-1: plasminogen activator inhibitor-1; VWF: vn Willebrand factor.