Plasma vitamin D and parathormone are associated with obesity and atherogenic dyslipidemia: a cross-sectional study

Guasch, Alba; Bulló, Mònica; Rabassa, Antoni; Bonada, Anna; Del Castillo, Daniel; Sabench, Fàtima; Salas-Salvadó, Jordi

doi:10.1186/1475-2840-11-149

Cardiovascular Diabetology

Table 4 Predictors of PTH and 25(OH)D by multiple regression analysis

From: Plasma vitamin D and parathormone are associated with obesity and atherogenic dyslipidemia: a cross-sectional study

Model 1	β	95% CI	P*	R²	Model 2	β	95% CI	P*	R²
PTH (pmol/L) (n=229)					PTH (pmol/L) (n=180)
BMI (kg/m²)	0.331	0.045, 0.119	<0.001		BMI (kg/m²)	0.291	0.032 – 0.129	0.001
Age (years)	0.263	0.025, 0.079	<0.001		Age (years)	0.187	0.007, 0.070	0.018
Gender	0.050	−0.471, 1.097	0.433		Gender	0.062	−0.609, 1.438	0.425
c-HDL (mmol/L)	−0.162	−1.959, -0.129	0.026		c-HDL (mmol/L)	−0.171	−2.403, -0.029	0.045
c-LDL (mmol/L)	0.077	−0.140, 0.584	0.228	0.211	c-LDL (mmol/L)	0.067	−0.235, 0.625	0.373
TG (mmol/L)	−0.093	−0.851, 0.141	0.159		TG (mmol/L)	−0.134	−1.114, 0.103	0.103	0.146
Glucose (mmol/L)	−0.092	−0.301, 0.058	0.183		Glucose (mmol/L)	−0.077	−0.308, 0.110	0.350
Seasonality	−0.138	−1.415, -0.102	0.024		Seasonality	−0.101	−1.316, 0.221	0.162
Hypertension	0.031	−0.735, 1.168	0.654		Hypertension	0.044	−0.803, 1.420	0.584
					CRP (mg/dL)	−0.034	−0.060, 0.039	0.672
					Leucocyte count (x10E9/L)	0.027	−0.153, 0.218	0.731
25(OH)D (nmol/L) (n=234)					25(OH)D (nmol/L) (n=186)
BMI (kg/m²)	−0.324	−2.103, -0.801	<0.001		BMI (kg/m²)	−0.238	−1.357, -0.212	0.008
Seasonality	−0.151	−25.459, -2.834	0.014		CRP (mg/dL)	−0.195	−1.289, -0.133	0.016
Age (years)	0.032	−0.341, 0.560	0.633		Age (years)	0.013	−0.334, 0.395	0.869
Gender	−0.112	−25.299, 1.781	0.088		Gender	−0.039	−15.284, 9.172	0.622
c-HDL (mmol/L)	0.079	−7.362, 25.292	0.280	0.171	c-HDL (mmol/L)	0.010	−13.590, 15.323	0.906
c-LDL (mmol/L)	−0.007	−6.617, 5.911	0.912		c-LDL (mmol/L)	−0.114	−8.973, 1.195	0.133	0.120
TG (mmol/L)	−0.081	−13.394, 3.268	0.232		TG (mmol/L)	−0.088	−10.637, 3.121	0.282
Glucose (mmol/L)	0.017	−2.624, 3.347	0.812		Glucose (mmol/L)	0.076	−1.251, 3.478	0.354
Hypertension	0.014	−15.052, 18.421	0.843		Seasonality	−0.130	−17.153, 0.731	0.072
					Hypertension	−0.030	−15.748, 10.713	0.708
					Leucocyte count (x10E9/L)	0.109	−0.652 – 3.745	0.167

* P value by multiple regression analysis.
Abbreviations: PTH Parathormone; BMI: Body Mass Index; 25(OH)D: 25.Hydroxy-cholecalcipherol CRP: C Reactive Protein.
Model 1. Potential predictors are age, gender, BMI, c-HDL, c-LDL, TG, glucose, season and presence of hypertension.
Model 2. Potential predictors are age, gender, BMI, c-HDL, c-LDL, TG, glucose, season, presence of hypertension, CRP and leucocyte count.

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ISSN: 1475-2840

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