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Table 2 Characteristics of patients according to body mass index (kg/m 2 ) ranges

From: Plasma vitamin D and parathormone are associated with obesity and atherogenic dyslipidemia: a cross-sectional study

 

BMI (Kg/m2)

 

<30 (n=50)

30-35 (n=45)

35-40 (n=45)

40-45 (n=81)

45-50 (n=53)

>50 (n=42)

P*

Age (years)

45.2 (40.2, 50.2)

53.0 (49.3, 56.7) #

44.8 (41.4, 48.3)

45.99 (43.5, 48.5)

46.1 (42.9, 49.2)

47.3 (44.3, 50.4)

0.022

Women

60.8%

60.0%

80.0%

82.7%

84.9%

83.3%

0.002

Weight (Kg)

66.6 (63.3, 69.9)

87.2 (84.4, 90.1) ##

99.5 (95.9, 103.1) ##

112.2 (109.4, 114.9) ##

122.2 (118.5, 125.8) ##

143.1 (136.2, 145.00) ##

<0.001

BMI (Kg/m2)

24.9 (23.9, 26.00)

32.4 (31.9, 32.8) ##

37.3 (36.8, 37.7) ##

42.7 (42.4, 43.0) ##

47.2 (46.8, 47.6) ##

55.2 (53.5, 56.8) ##

<0.001

Presence of MetS

19.6%

35.6%

57.8%

79.0%

79.2%

92.9%

<0.001

 Abdominal obesity

0.0%

4.4%

100.0%

100.0%

100.0%

100.0%

<0.001

 Elevated blood pressure

59.2%

83.3%

78.8%

93.5%

92.7%

93.9%

<0.001

 Elevated fasting glucose

31.4%

55.8%

45.5%

60.0%

63.5%

78.6%

<0.001

 Reduced HDL cholesterol

14.0%

50.0%

60.5%

76.6%

80.4%

83.3%

<0.001

 Elevated fasting triglycerides

25.5%

39.0%

27.9%

25.0%

35.5%

33.3%

0.556

Systolic blood pressure (mmHg)

136.4 (128.5, 144.3)

141.4 (136.00, 146.8)

133.8 (127.4, 140.2)

142.4 (137.5, 147.4)

141.5 (136.1, 147.0)

144.2 (136.2, 152.2)

0.244

Diastolic blood pressure (mmHg)

80.1 (76.6, 83.7)

85.6 (81.8, 89.3)

82.4 (77.9, 87.00)

85.3 (82.5, 88.2)

84.4 (80.2, 88.7)

87.0 (82.8, 91.2)

0.087

Glucose (mmol/L)

5.34 (4.88, 5.79)

6.05 (5.59, 6.51)

5.80 (5.35, 6.26)

6.08 (5.63, 6.53)

6.13 (5.59, 6.68)

7.09 (6.21, 7.97) ##

0.002

HDL cholesterol (mmol/L)

1.60 (1.47, 1.73)

1.21 (1.11, 1.32) ##

1.24 (1.11, 1.36) ##

1.12 (1.05, 1.20) ##

1.07 (0.97, 1.18) ##

1.10 (1.02, 1.17) ##

<0.001

LDL cholesterol (mmol/L)

2.87 (2.58, 3.16)

3.27 (2.95, 3.59)

3.45 (3.18, 3.72)

3.19 (3.01, 3.36)

3.32 (3.05, 3.59)

3.23 (2.93, 3.53)

0.070

Triglycerides (mmol/L)

1.26 (0.99, 1.54)

1.56 (1.25, 1.87)

1.54 (1.13, 1.95)

1.43 (1.28, 1.58)

1.61 (1.40, 1.82)

1.52 (1.26, 1.77)

0.464

ALAT (μKat/L)

0.35 (0.29, 0.41)

0.32 (0.30, 0.35)

0.35 (0.32, 0.38)

0.36 (0.33, 0.39)

0.38 (0.31, 0.45)

0.40 (0.34, 0.45)

0.430

GT (μKat/L)

0.27 (0.21, 0.32)

0.45 (0.27, 0.63)

0.47 (0.35, 0.59)

0.48 (0.38, 0.59)

0.44 (0.37, 0.50)

0.48 (0.39, 0.57)

0.131

Leucocyte count (x10E9/L)

6.08 (5.47, 6.70)

6.17 (5.65, 6.70)

7.93 (7.12, 8.74) #

7.99 (7.53, 8.44) ##

8.26 (7.66, 8.86) ##

8.63 (8.01, 9.25) ##

<0.001

Albumin (g/L)

47.0 (45.5, 48.5)

41.9 (40.4, 43.3) ##

40.6 (39.4, 41.8) ##

38.8 (38.00, 39.6) ##

38.4 (37.3, 39.5) ##

38.8 (37.5, 40.1) ##

<0.001

CRP ultrasensitive (mg/dL)

2.67 (1.90, 3.45)

4.17 (2.71, 5.63)

7.75 (5.81, 9.68)

9.35 (7.27, 11.44) #

11.16 (8.77, 13.54) #

16.80 (13.07, 20.53) ##

<0.001

ESR (mm/h)

14.50 (10.15, 18.85)

18.74 (14.56, 22.92)

18.38 (13.70, 23.05)

21.03 (17.93, 24.12)

26.95 (21.94, 31.96) #

34.84 (27.16, 42.52) ##

<0.001

25(OH)D (nmol/L)

95.8 (76.0, 115.5)

59.1 (48.5, 69.7) ##

48.2 (42.3, 54.0) ##

49.8 (42.6, 57.1) ##

46.6 (40.0, 53.2) ##

37.6 (30.3, 44.8) ##

<0.001

PTH (pmol/L)

4.27 (3.61, 4.93)

5.11 (4.50, 5.72)

5.84 (5.07, 6.61)

6.05 (5.50, 6.60) #

6.39 (5.68, 7.10) #

7.41 (6.31, 8.52) ##

<0.001

Calcium (mmol/L)

2.38 (2.34, 2.41)

2.32 (2.29, 2.35)

2.32 (2.30, 2.35)

2.33 (2.31, 2.35)

2.33 (2.31, 2.36)

2.34 (2.31, 2.36)

0.046

Phosphate (mmol/L)

1.20 (1.12, 1.27)

1.11 (1.03, 1.19)

1.19 (1.13, 1.26)

1.14 (1.10, 1.18)

1.17 (1.11, 1.22)

1.16 (1.10, 1.21)

0.374

Alkaline phosphatase (uKat/L)

1.14 (1.04, 1.25)

1.13 (1.02, 1.24)

1.30 (1.15, 1.46)

1.23 (1.10, 1.35)

1.21 (1.03, 1.38)

1.42 (1.19, 1.64)

0.132

eGFR (ml/min/1.73m2)

105.1 (99.3, 110.8)

99.1 (91.6, 106.6)

101.9 (97.1, 106.6)

105.0 (101.7, 108.4)

103.2 (98.0, 108.5)

102.4 (96.7, 108.1)

0.627

  1. Data are means (CI) for continuous variables and % for categorical variables.
  2. *P value by one-way analysis of variance (ANOVA) for continuous variables, and chi-square test (χ2) for categorical variables.
  3. # Statistical significance compared to the first BMI group (BMI<30 Kg/m2): #P <0.05 and ##P <0.001 by ANOVA, Bonferroni posthoc test.
  4. Abbreviations: BMI: Body Mass Index; MetS: Metabolic Syndrome; HDL: High Density Lipoprotein; LDL: Low Density Lipoprotein; ALAT: Alanine transaminase; GT: Glutamyl transaminase; uCRP: ultrasensitive C Reactive Protein; ESR: Erythrocyte Sedimentation Rate; PTH Parathormone; 25(OH)D; 25.Hydroxy-cholecalcipherol; eGFR: Estimated Glomerular Filtration Rate.
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Cardiovascular Diabetology

ISSN: 1475-2840