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Table 1 Clinical demographics in patients with and without impaired strains

From: Myocardial dysfunction in patients with type 2 diabetes mellitus: role of endothelial progenitor cells and oxidative stress

Variables

All patients (n = 87)

Longitudinal strain (cutoff −17.1%)

Circumferential strain (cutoff −17.0%)

Radial strain (cutoff 29.4%)

Preserved (n = 53)

Impaired (n = 34)

Preserved (n = 53)

Impaired (n = 34)

Preserved (n = 62)

Impaired (n = 25)

Age, years

61.8 ± 9.3

60.5 ± 9.7

63.9 ± 8.2

61.4 ± 10.1

62.5 ± 7.9

61.3 ± 9.7

62.9 ± 8.3

Male gender, % (n)

39.6(36)

42.9(24)

34.3(12)

33.9(19)

48.6(17)

59.7(37)

64.0(16)

BMI, kg/m2

25.7 ± 4.3

*25.01 ± 4.2

26.9 ± 4.2

25.3 ± 4.0

26.3 ± 4.7

25.2 ± 4.4

26.9 ± 4.2

SBP, mmHg

137 ± 16

137 ± 16

138 ± 16

138 ± 15

138 ± 17

136 ± 16

141 ± 16

DBP, mmHg

78 ± 8

78 ± 8

78 ± 8

77 ± 9

78 ± 7

77 ± 8

79 ± 8

Duration of disease, years

9.9 ± 7.7

8.9 ± 8.0

11.8 ± 7.0

8.9 ± 6.9

11.7 ± 8.9

10.4 ± 8.2

9.0 ± 7.2

Insulin therapy, % (n)

19.8(18)

*37.1(13)

8.9(5)

19.6(11)

20.0(7)

17.7(11)

24.0(6)

Smoker, % (n)

17.6(16)

17.9(10)

17.1(6)

16.1(9)

20.0(7)

14.5(9)

20.0(5)

Hypertension, % (n)

60.4(55)

57.1(32)

65.7(23)

57.1(32)

65.7(23)

61.3(38)

52.0(13)

Total cholesterol, mmol/L

4.9 ± 0.8

5.02 ± 0.90

4.83 ± 0.73

5.01 ± 0.85

4.84 ± 0.82

4.97 ± 0.86

4.95 ± 0.78

Triglycerides, mmol/L

1.4 ± 0.8

1.36 ± 0.80

1.42 ± 0.75

1.43 ± 0.79

1.31 ± 0.77

1.32 ± 0.77

1.53 ± 0.81

High density lipoprotein, mmol/L

1.4 ± 0.4

1.39 ± 0.37

1.44 ± 0.45

1.40 ± 0.36

1.42 ± 0.45

1.42 ± 0.45

1.40 ± 0.24

Low density lipoprotein, mmol/L

2.9 ± 0.7

3.01 ± 0.75

2.72 ± 0.62

2.95 ± 0.70

2.83 ± 0.74

2.93 ± 0.71

2.86 ± 0.72

Fasting glucose, mmol/L

7.57 ± 2.07

7.19 ± 1.78

8.11 ± 2.34

7.49 ± 2.31

7.68 ± 1.68

7.68 ± 2.19

7.52 ± 1.70

Creatinine, umol/L

77.1 ± 25.1

76.8 ± 27.58

77.6 ± 21.1

77.3 ± 28.5

76.8 ± 19.0

74.1 ± 15.9

77.1 ± 23.6

hs-CRP, mg/L

1.49 ± 2.18

1.36 ± 1.75

1.72 ± 2.80

1.65 ± 2.71

1.27 ± 0.98

1.33 ± 1.68

1.90 ± 3.09

SOD, U/ml

0.17 ± 0.08

0.18 ± 0.09

0.15 ± 0.06

**0.20 ± 0.08

0.13 ± 0.06

0.17 ± 0.09

0.16 ± 0.08

HbA1c, %

7.72 ± 1.24

*7.51 ± 1.22

8.07 ± 1.20

7.70 ± 1.21

7.75 ± 1.30

7.83 ± 1.32

7.54 ± 1.00

CD34+ EPCs, %

3.38 ± 2.07

*3.74 ± 2.12

2.82 ± 1.87

**3.87 ± 2.10

2.63 ± 1.80

*3.69 ± 1.99

2.62 ± 2.08

CD133+ EPCs, %

0.44 ± 0.45

0.44 ± 0.47

0.45 ± 0.43

0.50 ± 0.49

0.35 ± 0.38

0.46 ± 0.47

0.41 ± 0.42

CD34+/KDR + EPCs, %

0.85 ± 0.69

0.89 ± 0.57

0.78 ± 0.85

0.92 ± 0.78

0.74 ± 0.52

0.91 ± 0.75

0.70 ± 0.49

CD133+/KDR + EPCs, %

0.25 ± 0.28

0.25 ± 0.30

0.25 ± 0.28

0.28 ± 0.32

0.21 ± 0.20

0.28 ± 0.32

0.19 ± 0.14

  1. * P < 0.05; ** P < 0.01.
  2. Abbreviations: BMI = body mass index; EPCs = endothelial progenitor cells; DBP = diastolic blood pressure; hs-CRP = High sensitivity C-reactive protein; SBP = systolic blood pressure; SOD = superoxide dismutase.