Table 2 Changes of variables related with glucose metabolism after 12 weeks
Baseline (mean±s.d.) | 12 weeks (mean±s.d.) | Mean changes from baseline (95% CI) | ★Difference in mean change (95% CI) | |
|---|---|---|---|---|
HbA1c (%) | ||||
Liraglutide added | 8.79 ± 0.86 | 6.88 ± 0.64 | -1.9 (-2.10, -1.72) ** | -0.14 (-0.41, 0.13) |
Insulin increaing | 8.69 ± 0.91 | 6.93 ± 0.63 | -1.77 (-2.00, -1.56) ** | |
PBG (mmol/L) | ||||
Liraglutide added | 8.36 ± 0.93 | 6.79 ± 0.48 | -1.56 (-1.80, -1.33) ** | 0.13 (0.15, -0.16) |
Insulin increasing | 8.41 ± 0.86 | 6.72 ± 0.46 | -1.69 (-1.90, -1.48) ** | |
P2BG (mmol/L) | ||||
Liraglutide added | 13.76 ± 1.92 | 8.39 ± 1.17 | -5.40 (-5.8, -4.92) ** | -0.83 (-1.59, -0.07) # |
Insulin increasing | 13.80 ± 1.96 | 9.26 ± 1.19 | -4.54 (-5.0, -4.0) ** | |
Body weight (kg) | ||||
Liraglutide added | 88.6 ± 11.8 | 82.9 ± 11.2 | -5.62 (-6.51, -4.73) ** | -7.6 (-8.67, -6. 57) ## |
Insulin increasing | 86.3 ± 10.3 | 88.3 ± 10.4 | 2.00 (1.52, 2.48) ** | |
BMI (kg/m2) | ||||
Liraglutide added | 30.4 ± 3.21 | 28.4 ± 3.04 | -1.93 (-2.24, -1.63) ** | -2.63 (-2.99, -2.67) ## |
Insulin increasing | 30.3 ± 2.98 | 31.00 ± 2.91 | 0.70 (0.53, 0.86) ** | |
Waist Circumference (cm) | ||||
Liraglutide added | 105.6 ± 12.6 | 99.9 ± 11.8 | -5.70 (-6.5, -5.0) ** | -7.5 (-8.4, -6.6) ## |
Insulin increasing | 104.6 ± 10.5 | 106.3 ± 10.4 | 1.76 (1.30, 2.23) ** |