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Table 3 Cox proportional hazard analysis for total mortality by degree of glycemic control among type 2 diabetes patients according to the SNP rs2383206 genotype after a median follow-up of 9.5 years

From: Association between 9p21 genetic variants and mortality risk in a prospective cohort of patients with type 2 diabetes (ZODIAC-15)

Genotype

N of patients (deceased)

Hazard ratio total mortalitya

HbA1c 1st tertile (≤6.7%)

HbA1c 2nd tertile (6.7%-7.7%)

HbA1c 3rd tertile (≥7.7%)

rs2383206

AA/AG

674 (252)

1

1

1

GG

222 (96)

1.68 (1.08-2.62)

1.49 (1.01-2.19)

0.92 (0.60-1.41)

Missing

18 (10)

p=0.02

p=0.04

p=0.71

  1. a Corrected for age and sex.