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Table 2 Characteristics of myofilament force production in the skinned strip and of native thin filament (NTF) velocity in the myosin motility assay

From: Zinc-induced cardiomyocyte relaxation in a rat model of hyperglycemia is independent of myosin isoform

 

HG (n=6)

nonHG (6)

Tmin (mN/mm2)

4.24 ± 0.33

4.87 ± 0.18

Tmax (mN/mm2)

15.8 ± 1.4

16.9 ± 1.7

Tdev (mN/mm2)

11.6 ± 1.6

12.1 ± 1.8

pCa50

5.88 ± 0.02

5.89 ± 0.02

nHill

3.41 ± 0.38

3.06 ± 0.16

 

(n=3)

(3)

VCa, NTF (µm/s)

4.52 ± 0.30

4.62 ± 0.29

pCa50, NTF

6.35 ± 0.07

6.32 ± 0.06

nHill, NTF

1.36 ± 0.22

1.39 ± 0.23

  1. Tmin= minimum tensile stress, Tdev = developed tensile stress, pCa50 = pCa at 50% calcium activation, nHill = Hill coefficient, VCa, NTF = calcium-dependent NTF velocity.
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Cardiovascular Diabetology

ISSN: 1475-2840