Table 1 Rat model characteristics, echo morphometry and serum glucose
| Â | HG (n=8) | nonHG (8) |
|---|---|---|
Age (wks) | 19.8 ± 0.3 | 20.1 ± 0.4 |
PTU diet (wks) | 12.8 ± 0.3 | 13.1 ± 0.4 |
Body mass (g) | 217 ± 5 †| 278 ± 15 |
Glucose 1 wks (mg/dL) | 287 ± 20 | no measure |
Glucose 6 wks (mg/dL) | 422 ± 21 ††| 75 ± 6 |
Heart rate (bpm) | 213.3 ± 9.1 | 229.1 ± 5.0 |
LVD dias (mm) | 6.99 ± 0.18 | 6.88 ± 0.26 |
LVD sys (mm) | 4.40 ± 0.16 | 4.41 ± 0.25 |
Fractional Shortening (%) | 37.0 ± 1.7 | 35.9 ± 2.3 |
Ejection Fraction (%) | 74.7 ± 1.9 | 73.0 ± 2.7 |
Ejection Time (ms) | 146.6 ± 5.6 # | 135.8 ± 2.7 |
Circum. Velocity (circ/s) | 2.56 ± 0.17 | 2.67 ± 0.21 |
LVPWT dias (mm) | 1.35 ± 0.09 | 1.23 ± 0.09 |