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Table 4 Individual SNPs associated with waist circumference or insulin resistance in GWAS in relation to MetS and MetS-score

From: Single nucleotide polymorphisms (SNPs) involved in insulin resistance, weight regulation, lipid metabolism and inflammation in relation to metabolic syndrome: an epidemiological study

  MetS MetS-score
n 1886 1886
WC   
FTO rs1421085 1.02(0.93; 1.12) 0.05(−0.03; 0.14)
MC4Rrs17782313 1 1.16(1.02; 1.32) 0.10(−0.05; 0.24)
IR   
PPARG rs1801282 1.04(0.91; 1.19) 0.10(−0.02; 023)
IRS1 rs2943634 0.88(0.79; 0.97) −0.14(−0.23;-0.06)
GCKR rs780094 0.99(0.89; 1.09) 0.05(−0.04; 0.13)
IGF1 rs35767 1.03(0.91; 1.16) 0.03(−0.08; 0.14)
GCK rs1799884 1.07(0.95; 1.20) 0.08(−0.03; 0.22)
  1. Data are presented as PR per minor allele for MetS and as minor allele change for MetS Score; Mets Metabolic syndrome, WC waist circumference, IR insulin resistance.
  2. All analyses are adjusted for age, sex and cohort.
  3. 1Data available in 853 women.