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Table 1 SNPs included in the analyses of random sample of EPIC-NL (n=1886)

From: Single nucleotide polymorphisms (SNPs) involved in insulin resistance, weight regulation, lipid metabolism and inflammation in relation to metabolic syndrome: an epidemiological study

Gene SNP (literature) SNP (dataset) MAF (dataset) ref r2SNPs
Insulin resistance
PPARG rs1801282 rs1801282 G: 0.13 [14] -
IRS1 rs2943634 rs2943634 A: 0.35 [15] -
GCKR rs780094 rs780094 T: 0.37 [14] -
IGF1 rs35767 rs35767 A: 0.16 [14] -
GCK rs4607517 rs1799884 T: 0.18 [14] 1
Abdominal obesity
FTO rs1421085 rs1421085 C: 0.40 [16] -
MC4R 1 rs17782313 rs17782313 C: 0.25 [16] -
Inflammation
IL6R rs4537545 rs4537545 T: 0.39 [17] -
LEPR rs6700896 rs1805096 A: 0.38 [17] 0.89
CRP rs7553007 rs1341665 A: 0.32 [17] 1
ADIPOQ rs1648707 rs182052 A: 0.34 [18] 1
IL18 rs1834481 rs5744256 G: 0.26 [19] 1
GCKR rs780094 rs780094 T: 0.37 [20] -
Triglycerides
AFF1 rs442177 rs3775214 G: 0.43 [21] 0.96
APOB rs673548 rs673548 A: 0.22 [22] -
APOB rs693 rs693 G: 0.50 [23] -
APOA5-A4-C3-A1 rs12286037 rs12286037 T: 0.08 [24] -
APOA5 rs6589566 rs2075290 C: 0.06 [25] 1
FADS1 rs174548 rs174548 G: 0.29 [21]  
FADS1-2-3 rs174547 rs174577 A: 0.35 [26] 1
GALNT2 rs4846914 rs4846914 G: 0.41 [23] -
LPL rs328 rs328 G: 0.10 [23] -
MLXIPL rs17145738 rs17145750 T: 0.16 [24] 0.86
PLTP rs7679 rs6073952 A: 0.20 [26] 0.82
TRIB1 rs2954029 rs2954029 T: 0.47 [26] -
CLIP2 rs16996148 rs16996148 T: 0.10 [24] -
GCKR rs780094 rs780094 T: 0.37 [27] -
ANGPTL3-DOCK7 rs1748195 rs1748197 A: 0.35 [24] 1
ANGPTL3-DOCK7 rs12130333 rs12130333 T: 0.24 [23] -
HDL cholesterol
ABCA1 rs1883025 rs1883025 T: 0.24 [26] -
ABCA1 rs3890182 rs3890182 A: 0.10 [21] -
APOB rs11902417 rs11902417 A: 0.24 [21] -
CETP rs1800775 rs1800775 A: 0.46 [28] -
CETP rs3764261 rs3764261 A: 0.31 [29] -
FADS1 rs174548 rs174548 G: 0.29 [21] -
FADS1-2-3 rs174547 rs174577 A: 0.35 [26] -
GALNT2 rs4846914 rs4846914 G: 0.41 [23] -
LCAT rs255052 rs255052 A: 0.17 [24] -
LCAT rs12449157 rs1109166 C: 0.18 [21] 0.94
LIPC rs1800588 rs1800588 T: 0.22 [23] -
LIPG rs2156552 rs2156552 A: 0.16 [21] -
LPL rs328 rs328 G: 0.10 [23] -
PLTP rs7679 rs6073952 A: 0.20 [26] 0.82
MMAB MVK rs2338104 rs10774708 A: 0.47 [26] 1
HNF4A rs1800961 rs1800961 T: 0.04 [26] -
  1. 1Data available in 853 women.