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Table 3 Oxidative stress parameters evaluated in cardiac tissue of control, OB, STZ and STZ-treated OB rats

From: Obestatin induced recovery of myocardial dysfunction in type 1 diabetic rats: underlying mechanisms

  NON-DIABETIC DIABETIC
  CTRL (n  = 12) OB (n  = 6) CTRL (n  = 14) OB (n  = 14)
ROS (U.F./mg prot) 106.67 ± 2.08 106.54 ± 15.44 165.67 ± 15.40* 116.43 ± 18.02
GSSG/GSH (%) 1.60 ± 1.00 1.64 ± 0.40 8.91 ± 2.60*** 4.43 ± 3.20
HNE (μM) 0.80 ± 0.08 0.83 ± 0.08 1.79 ± 0.12** 1.02 ± 0.17††
  1. Values are expressed as means ± SD. Statistical significance: * P < 0.05 vs ND-CTRL; ** P < 0.01 vs ND-CTRL; *** P < 0.005 vs ND-CTRL; † P < 0.05 vs DM-CTRL; †† P < 0.01 vs DM-CTRL.