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Table 2 Body weight, heart weight, heart/body weight ratio, glucose, insulin level and lipid profile in plasma of untreated and OB-treated non-diabetic rats and in untreated and OB-treated diabetic rats, evaluated at the end of the protocol time (6 weeks)

From: Obestatin induced recovery of myocardial dysfunction in type 1 diabetic rats: underlying mechanisms

  NON-DIABETIC DIABETIC
  CTRL (n  = 12) OB (n  = 5) CTRL (n  = 14) OB (n  = 13)
BODY WEIGHT (g) 425 ± 14 344 ± 12* 258 ± 26** 233 ± 27**
HEART WEIGHT (g) 0.89 ± 0.06 0.88 ± 0.08 0.57 ± 0.05*** 0.52 ± 0.05***
HEART/BODY WEIGHT (g/mg) 2.63 ± 0.17 2.57 ± 0.07 3.20 ± 0.22** 3.09 ± 0.21*
GLUCOSE (mg/dL) 104 ± 18 99 ± 11 388 ± 27*** 372 ± 120***
INSULIN (μg/L) 0.42 ± 0.02 0.49 ± 0.05 0.18 ± 0.04*** 0.17 ± 0.03***
TG (mg/dL) 100.95 ± 6.69 102.26 ± 9.11 356.68 ± 57.03*** 255.09 ± 21.84**†
LDL (mg/dL) 56.78 ± 7.46 59.10 ± 9.22 169.19 ± 14.46*** 112.41 ± 11.98**†
HDL (mg/dL) 55.99 ± 5.50 54.26 ± 2.69 25.14 ± 3.38*** 40.89 ± 8.67*†
TC (mg/dL) 92.58 ± 3.29 92.91 ± 9.57 123.11 ± 16.68* 104.49 ± 5.41
  1. Values are expressed as means ± SD. Statistical significance: * P < 0.05 vs ND-CTRL; ** P < 0.01 vs ND-CTRL; *** P < 0.005 vs ND-CTRL; † P < 0.05 vs DM-CTRL.