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Table 2 Body weight, heart weight, heart/body weight ratio, glucose, insulin level and lipid profile in plasma of untreated and OB-treated non-diabetic rats and in untreated and OB-treated diabetic rats, evaluated at the end of the protocol time (6 weeks)

From: Obestatin induced recovery of myocardial dysfunction in type 1 diabetic rats: underlying mechanisms

 

NON-DIABETIC

DIABETIC

 

CTRL (n  = 12)

OB (n  = 5)

CTRL (n  = 14)

OB (n  = 13)

BODY WEIGHT (g)

425 ± 14

344 ± 12*

258 ± 26**

233 ± 27**

HEART WEIGHT (g)

0.89 ± 0.06

0.88 ± 0.08

0.57 ± 0.05***

0.52 ± 0.05***

HEART/BODY WEIGHT (g/mg)

2.63 ± 0.17

2.57 ± 0.07

3.20 ± 0.22**

3.09 ± 0.21*

GLUCOSE (mg/dL)

104 ± 18

99 ± 11

388 ± 27***

372 ± 120***

INSULIN (μg/L)

0.42 ± 0.02

0.49 ± 0.05

0.18 ± 0.04***

0.17 ± 0.03***

TG (mg/dL)

100.95 ± 6.69

102.26 ± 9.11

356.68 ± 57.03***

255.09 ± 21.84**†

LDL (mg/dL)

56.78 ± 7.46

59.10 ± 9.22

169.19 ± 14.46***

112.41 ± 11.98**†

HDL (mg/dL)

55.99 ± 5.50

54.26 ± 2.69

25.14 ± 3.38***

40.89 ± 8.67*†

TC (mg/dL)

92.58 ± 3.29

92.91 ± 9.57

123.11 ± 16.68*

104.49 ± 5.41†

  1. Values are expressed as means ± SD. Statistical significance: * P < 0.05 vs ND-CTRL; ** P < 0.01 vs ND-CTRL; *** P < 0.005 vs ND-CTRL; † P < 0.05 vs DM-CTRL.