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Table 4 Determinants of vascular measurements (FMD, NMD and PWV) in multivariate analysis

From: Determinants of vascular function in patients with type 2 diabetes

  Multivariate analysis
B (95% CI) P
FMD, % Time since diagnosis of diabetes, years* −0.40 (−0.66, -0.14) 0.003
NMD, % Age, years* −5.66 (−9.49, -1.82) 0.004
Hypertension −1.80 (−3.25, -0.35) 0.015
Fasting glucose, μmol/L −0.36 (−0.54, -0.18) 0.005
PWV, m/sec Age, years* 6.22 (3.81, 8.63) <0.001
Systolic blood pressure, mmHg 0.03 (0.00, 0.05) 0.032
  1. *Natural logarithm transformed variables. FMD, flow-mediated dilation of the brachial artery; NMD, nitrate-mediated dilation of the brachial artery; PWV, carotid-femoral pulse wave velocity.
  2. The independent variables included in the stepwise model were parameters whose association with the vascular parameters achieved statistical significance (P < 0.05) and other factors that may affect endothelial dysfunction and arterial stiffness (age, gender, heart rate, systolic blood pressure and use of antihypertensive medications).