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Table 4 Determinants of vascular measurements (FMD, NMD and PWV) in multivariate analysis

From: Determinants of vascular function in patients with type 2 diabetes

 

Multivariate analysis

B (95% CI)

P

FMD, %

Time since diagnosis of diabetes, years*

−0.40 (−0.66, -0.14)

0.003

NMD, %

Age, years*

−5.66 (−9.49, -1.82)

0.004

Hypertension

−1.80 (−3.25, -0.35)

0.015

Fasting glucose, μmol/L

−0.36 (−0.54, -0.18)

0.005

PWV, m/sec

Age, years*

6.22 (3.81, 8.63)

<0.001

Systolic blood pressure, mmHg

0.03 (0.00, 0.05)

0.032

  1. *Natural logarithm transformed variables. FMD, flow-mediated dilation of the brachial artery; NMD, nitrate-mediated dilation of the brachial artery; PWV, carotid-femoral pulse wave velocity.
  2. The independent variables included in the stepwise model were parameters whose association with the vascular parameters achieved statistical significance (P < 0.05) and other factors that may affect endothelial dysfunction and arterial stiffness (age, gender, heart rate, systolic blood pressure and use of antihypertensive medications).
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Cardiovascular Diabetology

ISSN: 1475-2840