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Table 1 Changes of serum and cardiac FFA composition in CON and DM groups (n = 12)

From: Reduction of n-3 PUFAs, specifically DHA and EPA, and enhancement of peroxisomal beta-oxidation in type 2 diabetic rat heart

Fatty acid        Serum (μmol/ml)        Heart (μmol/g prot)
CON DM CON DM
C16:0(palmitic acid) 324 ± 21 453 ± 56 ** 1481 ± 108 1593 ± 118
C18:0(octadecanoic acid) 202 ± 22 334 ± 31 ** 2193 ± 197 2835 ± 129**
C20:0(arachidic acid) 3.9 ± 0.2 5.1 ± 0.2 * 13.0 ± 1.1 14.4 ± 1.3
C22:0(behenic acid) 4.7 ± 0.4 7.5 ± 0.9 ** 21.9 ± 1.5 21.7 ± 2.9
C24:0(lignoceric acid) 9.1 ± 1.7 8.8 ± 0.7 36.4 ± 4.7 26.0 ± 1.6**
C16:1n-7(palmitoleic acid) 13.1 ± 1.8 12.2 ± 3.0 42.6 ± 10.8 41.5 ± 4.3
C18:1n-9(oleic acid, OA) 83.4 ± 23.3 259 ± 69 ** 859 ± 113 1994 ± 209**
C18:2n-6(linoleic acid, LA) 255 ± 28 231 ± 20 1473 ± 99 1724 ± 229**
C20:4n-6(arachidonic acid, AA) 227 ± 15 250 ± 19 1330 ± 130 1318 ± 145
C22:4n-6(docosatetraenoic acid) 1.4 ± 1.1 10.0 ± 1.3** 49.5 ± 8.1 127 ± 11**
C18:3n-3(α-linolenic acid, LNA) 7.4 ± 0.7 2.8 ± 0.4 ** 20.5 ± 6.5 11.3 ± 2.2**
C20:5n-3(eicosapentaenoic acid, EPA) 10.1 ± 1.1 8.2 ± 0.5 ** 10.0 ± 1.4 ND
C22:5n-3(docosapentaenoic acid, DPA) 3.6 ± 1.3 3.5 ± 1.3 81.7 ± 7.5 47.2 ± 6.9**
C22:6n-3(docosahexaenoic acid, DHA) 47.4 ± 2.1 50.6 ± 3.8 613 ± 62 317 ± 61**
n-6/n-3 7.1 7.9 3.9 8.4
  1. Data represent the means ± SD. * P < 0.05 vs. CON; ** P < 0.01 vs. CON. ND: not detected.