Table 1 Patient characteristics, laboratory values at baseline and co-morbid disease conditions
Age ≥ 70 years | Age < 70 to ≥ 60 years | Age < 60 years | p-value* | |
|---|---|---|---|---|
(n=1,373) | (n=1,184) | (n=1,253) | ||
Median (IQR) or % | Median (IQR) or % | Median (IQR) or % | ||
Age (years) | 74.0 (72.0-78.0) | 65.0 (62.0-67.0) | 54.0 (49.0-57.0) | <0.0001 |
Women (%) | 51.1 | 45.9 | 42.5 | <0.0001 |
Diabetes duration (years) | 6.8 (3.9-10.6) | 6.0 (3.3-9.5) | 4.1 (1.9-7.3) | <0.0001 |
Physically active (any sport) | 31.0 | 42.9 | 47.8 | <0.0001 |
Body Mass Index (kg/m2) | 29.0 (26.0-33.0) | 31.0 (28.0-35.0) | 32.0 (28.0-36.0) | <0.0001 |
Men (kg/m2) | 29.0 (26.0-32.0) | 30.0 (27.0-33.0) | 31.0 (28.0-36.0) | <0.0001 |
Women (kg/m2) | 30.0 (27.0-34.0) | 32.0 (28.0-36.0) | 33.0 (29.0-38.0) | <0.0001 |
Waist circumference (cm) | 104 (96.0-113.0) | 108 (98–117) | 109 (99.0-120.0) | <0.0001 |
HbA1c (%) | 7.3 (6.8-7.9) | 7.5 (6.9-8.4) | 7.6 (6.9-8.9) | <0.0001 |
Fasting plasma glucose (mmol/l) | 7.7 (6.4-9.2) | 7.8 (6.7-9.4) | 8.1 (6.8-10.1) | <0.0001 |
Postprandial plasma glucose (mmol/l) | 10.0 (8.6-11.8) | 10.2 (8.4-12.2) | 10.5 (8.7-13.0) | <0.0001 |
Co-morbidity | ||||
Dyslipidemia | 64.9 | 65.5 | 59.3 | <0.01 |
Hypertension | 90.5 | 86.2 | 76.0 | <0.0001 |
Coronary heart disease | 28.1 | 16.0 | 8.5 | <0.0001 |
Myocardial infarction | 28.8 | 37.0 | 50.0 | <0.0001 |
Stable angina | 33.6 | 26.2 | 20.0 | <0.01 |
Unstable angina | 3.2 | 3.8 | 5.1 | 0.40 |
PCI | 35.2 | 44.1 | 52.5 | <0.001 |
Bypass surgery | 21.6 | 21.4 | 19.8 | 0.74 |
Prior stroke / TIA | 6.8 | 4.3 | 2.5 | <0.0001 |
Heart failure | 18.6 | 7.5 | 2.6 | <0.0001 |
Peripheral arterial disease | 8.2 | 6.4 | 3.2 | <0.0001 |
Amputation | 1.3 | 0.6 | 0.8 | 0.16 |
Autonomous neuropathy | 4.4 | 3.5 | 2.1 | <0.01 |
Peripheral neuropathy | 18.4 | 15.8 | 8.5 | <0.0001 |
NPDR | 5.2 | 3.5 | 2.4 | <0.001 |
Proliferative retinopathy | 1.0 | 0.4 | 0.1 | <0.01 |