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Table 4 Predictors of mediastinal adipokines mRNA expression in multiple linear regression analysis

From: The role of mediastinal adipose tissue 11β-hydroxysteroid d ehydrogenase type 1 and glucocorticoid expression in the development of coronary atherosclerosis in obese patients with ischemic heart disease

Mediastinal
adipokines mRNA expressions
Variables R2 Standardized β P Value
11β–HSD-1 mRNA expression MAT GCR mRNA levels 0.402 0.448 0.01
Cortisol 0.233 0.029
C:18:4n-3 0.189 0.064
HOMA-IR −0.190 0.509
GCR mRNA expression Weight 0.351 0.131 0.039
MAT 11β–HSD-1 mRNA levels 0.785 0.005
Cortisol −0.501 0.018
Weight 0.756 0.038
CD68 mRNA expression MAT 11β–HSD-1mRNA levels 0.564 0.480 0.004
MAT GCR mRNA levels 0.351 0.019
Cortisol 0.250 0.031
Weight 0.253 0.065
  1. Multiple linear regression analysis with 11β–HSD-1, GCR and CD68 mRNA expression in mediastinal adipose tissue, cortisol, weight.
  2. HOMA-IR and C:18:4n-3 as dependent variables and mediastinal adipokines mRNA expression in MAT as independent variables.
  3. MAT: mediastinal adipose tissue; GCR: glucocortcoid receptor; C:18:4n-3: stearidonic acid. P < 0.05; statistical significance.