| |
Obese CAD group (n = 31)
|
Controls (n = 16)
|
p value
|
|---|
|
Antropometric characteristics
| | | |
|
Age (years)
|
57.4 ± 9.1
|
58.1 ±10.4
|
NS
|
|
Female–male (%)
|
66-34
|
51-49
|
NS
|
|
BMI (kg/m
2
)
|
33.6 ± 3.1
|
30.0 ±5.2
|
NS
|
|
Waist/hip ratio
|
1.1 ± 0.0
|
0.8 ± 0.1
|
NS
|
|
Risk factors
| | | |
|
Smoking (%)
|
44
|
66
|
0.004
|
|
Family history of CAD (%)
|
62
|
25
|
0.0001
|
|
Metabolic characteristics and indices
| | | |
|
SBP (mm Hg)
|
135.9 ± 19.4
|
129.5 ± 30.2
|
NS
|
|
DBP (mm Hg)
|
78.5 ± 8.9
|
77.3 ± 8.1
|
NS
|
|
Total-cholesterol (mg/dl)
|
196.1 ± 31.9
|
200.1 ± 31.4
|
NS
|
|
HDL-cholesterol (mg/dl)
|
41.2 ± 9.0
|
45 ± 11.9
|
NS
|
|
LDL-cholesterol (mg/dl)
|
111.5 ± 19.0
|
142.4 ± 29.7
|
0.041
|
|
Triglycerides (mg/dl)
|
191.0 ± 21.5
|
201.1 ± 24.1
|
NS
|
|
Cortisol (μg/dl)
|
13.1 ± 4.5
|
8.2 ± 3.1
|
0.006
|
|
HOMA-IR
|
3.1 ± 1.6
|
1.9 ± 1.0
|
0.005
|
|
C-peptid (ng/ml)
|
2.6 ± 1.1
|
3.2 ± 1.2
|
NS
|
|
Epicardial fat (cm
3
)
|
8.8 ± 5.1
|
6.0 ± 2.5
|
0.001
|
|
Subcutaneous fat (cm
3
)
|
138.8 ± 44.1
|
133.1 ± 39.1
|
NS
|
- Values are represented as mean ± SD, or as percentages. SD: Standard deviation, BMI: Body mass index, SBP: Systolic blood pressure, DBP: Diastolic blood pressure, HDL: High density lipoprotein, LDL: Low density lipoprotein, HOMA-IR: Homeostasis Model of Assessment - Insulin Resistance. Groups were compared with Mann–Whitney U test for the variables.
