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Table 1 The antropometric, clinical and metabolic data of the study group

From: The role of mediastinal adipose tissue 11β-hydroxysteroid d ehydrogenase type 1 and glucocorticoid expression in the development of coronary atherosclerosis in obese patients with ischemic heart disease

 

Obese CAD group (n = 31)

Controls (n = 16)

p value

Antropometric characteristics

   

Age (years)

57.4 ± 9.1

58.1 ±10.4

NS

Female–male (%)

66-34

51-49

NS

BMI (kg/m 2 )

33.6 ± 3.1

30.0 ±5.2

NS

Waist/hip ratio

1.1 ± 0.0

0.8 ± 0.1

NS

Risk factors

   

Smoking (%)

44

66

0.004

Family history of CAD (%)

62

25

0.0001

Metabolic characteristics and indices

   

SBP (mm Hg)

135.9 ± 19.4

129.5 ± 30.2

NS

DBP (mm Hg)

78.5 ± 8.9

77.3 ± 8.1

NS

Total-cholesterol (mg/dl)

196.1 ± 31.9

200.1 ± 31.4

NS

HDL-cholesterol (mg/dl)

41.2 ± 9.0

45 ± 11.9

NS

LDL-cholesterol (mg/dl)

111.5 ± 19.0

142.4 ± 29.7

0.041

Triglycerides (mg/dl)

191.0 ± 21.5

201.1 ± 24.1

NS

Cortisol (μg/dl)

13.1 ± 4.5

8.2 ± 3.1

0.006

HOMA-IR

3.1 ± 1.6

1.9 ± 1.0

0.005

C-peptid (ng/ml)

2.6 ± 1.1

3.2 ± 1.2

NS

Epicardial fat (cm 3 )

8.8 ± 5.1

6.0 ± 2.5

0.001

Subcutaneous fat (cm 3 )

138.8 ± 44.1

133.1 ± 39.1

NS

  1. Values are represented as mean ± SD, or as percentages. SD: Standard deviation, BMI: Body mass index, SBP: Systolic blood pressure, DBP: Diastolic blood pressure, HDL: High density lipoprotein, LDL: Low density lipoprotein, HOMA-IR: Homeostasis Model of Assessment - Insulin Resistance. Groups were compared with Mann–Whitney U test for the variables.