Table 2 Six-month changes in vascular stiffness and risk factors during the SAVE trial
From: Effects of weight loss and insulin reduction on arterial stiffness in the SAVE trial
SAVE (N = 272) | |||
|---|---|---|---|
Vascular Stiffness | Mean | SD | % Change |
Δ ba PWV (cm/s), mixed | −11.6† | 91.5 | −0.7 |
Δ fa PWV (cm/s), peripheral | +5.8 | 91.9 | +0.9 |
Δ cf PWV (cm/s), central | −51.9† | 303.3 | −1.6 |
Potential Covariates | |||
Weight (kg) | −7.0 | 5.9 | −7.6 |
BMI (kg/m2) | −2.0 | 2.0 | −7.0 |
HDLc (mg/dL) | 0.9 | 8.0 | 3.1 |
LDLc (mg/dL) | −2.9 | 25.7 | −0.3 |
Triglycerides (mg/dL) | −18.7 | 60.1 | −9.1 |
CRP (mg/dL) | −1.0 | 4.9 | −38.0 |
Fasting Insulin (μU/mL) | −1.3 | 6.9 | −0.7 |
Systolic BP, mm Hg | −2.6 | 8.2 | −2.0 |
Diastolic BP, mm Hg | −1.5 | 7.7 | −1.4 |
Mean Arterial Pressure | −2.0 | 7.2 | −1.9 |