Table 1 Baseline risk factors and vascular stiffness in the SAVE trial
From: Effects of weight loss and insulin reduction on arterial stiffness in the SAVE trial
All (N = 339) | Women (N = 261) | Men (N = 78) | |||||
|---|---|---|---|---|---|---|---|
Risk Factor | Mean | SD | Mean | SD | Mean | SD | P-Value‡ |
Age (years) | 37.9 | 6.1 | 37.5 | 6.1 | 38.0 | 6.1 | 0.478 |
Weight (kg) | 92.2 | 15.0 | 88.3 | 12.6 | 105.1 | 15.3 | <0.001 |
BMI (kg/m2) | 32.8 | 3.9 | 32.6 | 3.9 | 33.5 | 3.7 | 0.062 |
Heart Rate (bpm) | 70.0 | 17.4 | 69.9 | 16.5 | 70.0 | 20.4 | 0.998 |
Total Cholesterol (mg/dL) | 203.3 | 37.4 | 203.5 | 38.0 | 202.7 | 35.7 | 0.876 |
HDLc (mg/dL) | 52.8 | 13.5 | 55.8 | 13.4 | 42.7 | 7.9 | <.001 |
LDLc (mg/dL) | 123.7 | 33.2 | 122.7 | 33.9 | 126.9 | 30.4 | 0.329 |
Triglycerides (mg/dL)† | 116 | (78–170) | 106 | (76–155) | 151 | (110–209) | <0.001 |
CRP (mg/dL)† | 2.6 | (1.3-5.7) | 2.9 | (1.5-6.5) | 2.2 | (0.9-3.6) | <0.001 |
Fasting Insulin (μU/mL) | 14.6 | 8.1 | 14.0 | 6.8 | 16.5 | 11.2 | 0.069 |
HOMA-IR | 3.6 | 2.1 | 3.4 | 1.8 | 4.1 | 2.9 | 0.045 |
Systolic BP, mm Hg | 113.3 | 10.5 | 112.2 | 10.6 | 117.1 | 9.1 | <.001 |
Diastolic BP, mm Hg | 72.9 | 8.7 | 71.8 | 8.6 | 76.5 | 8.1 | <.001 |
Mean Arterial Pressure | 93.1 | 8.9 | 92.0 | 8.9 | 96.8 | 7.9 | <.001 |
Ankle-Brachial Index | 1.06 | 0.07 | 1.05 | 0.07 | 1.08 | 0.07 | 0.002 |
Race – n,% | 0.013 | ||||||
White | 273 | 80.5% | 205 | 78.5% | 68 | 87.2% | |
Black | 54 | 15.9% | 49 | 18.8% | 5 | 6.4% | |
Other | 12 | 3.5% | 7 | 2.7% | 5 | 6.4% | |
Smoking Status – n,% | 0.067 | ||||||
Never | 211 | 62.2% | 155 | 59.4% | 56 | 71.8% | |
Former | 96 | 28.4% | 82 | 31.4% | 14 | 17.9% | |
Current | 32 | 9.4% | 24 | 9.2% | 8 | 10.3% | |
Vascular Stiffness | Mean | SD | Mean | SD | Mean | SD | |
Mixed, ba PWV (cm/sec) | 1207.6 | 132.3 | 1194.2 | 126.0 | 1252.3 | 143.6 | <.001 |
Peripheral, fa PWV (cm/sec) | 945.9 | 102.8 | 942.9 | 98.2 | 956.1 | 117.5 | 0.385 |
Central, cf PWV (cm/sec) | 880.0 | 257.4 | 864.6 | 247.8 | 932.3 | 283.1 | 0.046 |