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Table 1 Cardiovascular risk profiles according to quintiles of UACR in men

From: Higher normal ranges of urine albumin-to-creatinine ratio are independently associated with carotid intima-media thickness

  UACR, mg/g p*
< 6.50 6.5-9.79 9.80-13.49 13.50-18.89 ≥ 18.90
Number (%) 691 (22.4) 692 (22.4) 641 (20.8) 549 (17.8) 511 (16.6)  
Age, y 60.2 ± 8.0 61.0 ± 7.9 62.3 ± 7.4 63.4 ± 7.3 63.4 ± 7.2 < 0.001
Current smoker, % 29.8 35.0 39.6 33.4 33.1 0.287
Current drinker, % 63.6 62.4 66.7 66.9 67.5 0.043
Hypertension, % 31.8 33.7 33.0 41.2 47.0 < 0.001
Type 2 diabetes, % 8.0 8.7 9.8 13.5 16.3 < 0.001
Hyperlipidemia, % 6.5 6.1 7.2 6.7 7.8 0.331
Body mass index, kg/m2 24.0 ± 2.8 23.7 ± 2.7 23.8 ± 2.7 23.8 ± 2.9 24.1 ± 2.8 0.059
Waist circumference, cm 85.5 ± 7.6 84.4 ± 7.3 85.1 ± 7.8 84.7 ± 8.2 86.0 ± 7.8 0.004
Systolic BP, mmHg 121.1 ± 15.9 122.3 ± 15.1 124.3 ± 15.2 127.7 ± 16.2 129.6 ± 15.9 < 0.001
Diastolic BP, mmHg 79.6 ± 9.3 79.6 ± 9.6 79.9 ± 9.3 81.7 ± 9.9 82.1 ± 10.2 < 0.001
Total cholesterol, mmol/L 4.7 ± 0.9 4.7 ± 0.9 4.7 ± 0.9 4.7 ± 0.9 4.8 ± 1.0 0.246
Triglycerides, mmol/L 1.8 ± 1.4 1.7 ± 1.3 1.8 ± 1.3 1.8 ± 1.3 2.0 ± 1.4 < 0.001
HDL cholesterol, mmol/L 1.2 ± 0.3 1.2 ± 0.3 1.2 ± 0.3 1.2 ± 0.3 1.2 ± 0.3 0.727
FBG, mmol/L 5.7 ± 0.9 5.7 ± 0.9 5.7 ± 1.0 5.8 ± 1.1 6.1 ± 1.6 < 0.001
HOMA-IR 1.4 ± 1.3 1.2 ± 1.1 1.3 ± 1.4 1.2 ± 1.0 1.6 ± 1.9 < 0.001
Serum creatinine, μmol/L 91.5 ± 16.7 87.9 ± 13.3 87.4 ± 13.1 86.0 ± 13.6 86.9 ± 13.6 < 0.001
eGFR, ml/min/1.73m2 83.9 ± 13.0 86.9 ± 14.3 87.0 ± 14.0 88.5 ± 15.4 87.1 ± 14.1 < 0.001
  1. Data are expressed as mean ± standard deviation, unless otherwise indicated. BP, blood pressure; HDL; high-density lipoprotein, FBG, fasting blood glucose; HOMA-IR; homeostatic model assessment for insulin resistance, eGFR; estimated glomerular filtration rate.
  2. eGFR was calculated using the 6-variable Modification of Diet in Renal Disease (MDRD) formula.
  3. * p-values for analysis of variance (ANOVA) and chi-square tests for trends are shown, as appropriate.