Figure 2

Insulin sensitivity and glycemia of the animals studied, at 3, 6 and 9 months of age. C: Wistar-Kyoto rats that did not receive any treatment; H: spontaneously hypertensive rats that did not receive any treatment; MetS: spontaneously hypertensive rats that received MSG during the neonatal period. n = 6 in all groups. Painel A: Insulin sensitivity evaluated by the insulin tolerance test (ITT). Two-way analysis of variance (ANOVA): group (p<0.001), time (p = 0.062) and interaction (p = 0.022), followed by the Bonferroni’s post hoc test: * p<0.05 and *** p<0.001 vs. C; † p<0.05 vs. H at the same time. Painel B: Glycemia after 8 hours of food deprivation. Two-way analysis of variance (ANOVA): group (p = 0.001), time (p = 0.021) and interaction (p = 0.041), followed by the Bonferroni’s post hoc test: * p<0.05 vs. C at the same time.